Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on: January 22,2024

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on:January 22,2024

Direct-acting antivirals still underused in hep C-related liver cancer

by Lori SolomonDirect-acting antiviral agents (DAAs) remain underutilized in patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), according to a study presented at The Liver M

Updated on: April 10,2024

Direct-acting antivirals still underused in hep C-related liver cancer

by Lori SolomonDirect-acting antiviral agents (DAAs) remain underutilized in patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), according to a study presented at The Liver M

Updated on:April 10,2024

Molecular culprit behind virus-mediated chronic inflammation and cancers identified

by Public Library of ScienceBC-3 cells were stained with DAPI, anti-vFLIP, anti-CADM1, and cholera toxin B conjugated with red fluorescence to detect GM-1 and subjected to confocal microscopy. Cr

Updated on: March 01,2024

Molecular culprit behind virus-mediated chronic inflammation and cancers identified

by Public Library of ScienceBC-3 cells were stained with DAPI, anti-vFLIP, anti-CADM1, and cholera toxin B conjugated with red fluorescence to detect GM-1 and subjected to confocal microscopy. Cr

Updated on:March 01,2024

Unique approach to treatment of rare and aggressive blood cancers

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainA unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and dif

Updated on: April 10,2024

Unique approach to treatment of rare and aggressive blood cancers

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainA unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and dif

Updated on:April 10,2024

New research reveals devastating impact of COVID-19 on the diagnosis of oesophageal and stomach cancer

by Queen's University BelfastCredit: AI-generated imageNew research by Queen's University Belfast and the Northern Ireland Cancer Registry has highlighted the impact of the COVID-19 pande

Updated on: April 29,2024

New research reveals devastating impact of COVID-19 on the diagnosis of oesophageal and stomach cancer

by Queen's University BelfastCredit: AI-generated imageNew research by Queen's University Belfast and the Northern Ireland Cancer Registry has highlighted the impact of the COVID-19 pande

Updated on:April 29,2024

A curiosity-driven genetic discovery that should impact cancer treatments

by Trinity College DublinKiller T cells surround a cancer cell. Credit: NIHA team of geneticists with a desire to understand the inner workings of genes implicated in cellular identity has discov

Updated on: May 23,2024

A curiosity-driven genetic discovery that should impact cancer treatments

by Trinity College DublinKiller T cells surround a cancer cell. Credit: NIHA team of geneticists with a desire to understand the inner workings of genes implicated in cellular identity has discov

Updated on:May 23,2024

US regulators approve 2nd gene therapy for blood cancer

by Linda A. JohnsonIn this May 2016 file photo provided by Kite Pharma, cell therapy specialists at the company's manufacturing facility in El Segundo, Calif., prepare blood cells from a patient t

Updated on: March 12,2024

US regulators approve 2nd gene therapy for blood cancer

by Linda A. JohnsonIn this May 2016 file photo provided by Kite Pharma, cell therapy specialists at the company's manufacturing facility in El Segundo, Calif., prepare blood cells from a patient t

Updated on:March 12,2024

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on: March 12,2024

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on:March 12,2024

What do you know about these three rare childhood cancers?

by Laurel KellyCredit: Unsplash/CC0 Public DomainChildhood cancer rates have been rising slightly for the past few decades, and about 10,470 children in the U.S. under the age of 15 will be diagnosed

Updated on: January 02,2024

What do you know about these three rare childhood cancers?

by Laurel KellyCredit: Unsplash/CC0 Public DomainChildhood cancer rates have been rising slightly for the past few decades, and about 10,470 children in the U.S. under the age of 15 will be diagnosed

Updated on:January 02,2024

A combined PET-MRI scan could improve treatment for patients with early breast cancer

by European Organisation for Research and Treatment of CancerPhoto of researchers Dr. Rosa Di Micco & Professor Oreste Gentilini. Credit: EORTC / Rosa Di MiccoUsing a combined scanning technique o

Updated on: March 30,2024

A combined PET-MRI scan could improve treatment for patients with early breast cancer

by European Organisation for Research and Treatment of CancerPhoto of researchers Dr. Rosa Di Micco & Professor Oreste Gentilini. Credit: EORTC / Rosa Di MiccoUsing a combined scanning technique o

Updated on:March 30,2024

Study uncovers potential therapeutic approach for advanced prostate cancer

by Melissa Rohman,Northwestern UniversityPALI1 bridges the interaction between PRC2 (SUZ12/EZH2/EED) and G9A to catalyze dual H3K9 and H3K27 methylation, which leads to strong repression of GPS

Updated on: February 01,2024

Study uncovers potential therapeutic approach for advanced prostate cancer

by Melissa Rohman,Northwestern UniversityPALI1 bridges the interaction between PRC2 (SUZ12/EZH2/EED) and G9A to catalyze dual H3K9 and H3K27 methylation, which leads to strong repression of GPS

Updated on:February 01,2024

Researchers identify traits linked to better outcomes in HPV-linked head and neck cancer

by UNC Lineberger Comprehensive Cancer CenterUsing a new blood test that's in development, University of North Carolina Lineberger Comprehensive Cancer Center researchers identified character

Updated on: June 19,2024

Researchers identify traits linked to better outcomes in HPV-linked head and neck cancer

by UNC Lineberger Comprehensive Cancer CenterUsing a new blood test that's in development, University of North Carolina Lineberger Comprehensive Cancer Center researchers identified character

Updated on:June 19,2024