New drug targets for BRCA-driven cancer uncovered

by Brigham and Women's HospitalCredit: CC0 Public DomainBRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes h

Updated on: March 30,2024

New drug targets for BRCA-driven cancer uncovered

by Brigham and Women's HospitalCredit: CC0 Public DomainBRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes h

Updated on:March 30,2024

Study may explain why some triple-negative breast cancers are resistant to chemotherapy

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainTriple-negative breast cancer (TNBC) is an aggressive form of the disease accounting for 12 to 18 percent of breast can

Updated on: June 28,2024

Study may explain why some triple-negative breast cancers are resistant to chemotherapy

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainTriple-negative breast cancer (TNBC) is an aggressive form of the disease accounting for 12 to 18 percent of breast can

Updated on:June 28,2024

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on: February 18,2024

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on:February 18,2024

Investigating racial differences in multiple myeloma

by Melissa Rohman,Northwestern UniversityGenome-wide profiling of 5hmC from cfDNA derived from EA and AA patients with MM and its precursors. Genome-wide 5hmC was profiled in patient-derived pla

Updated on: January 22,2024

Investigating racial differences in multiple myeloma

by Melissa Rohman,Northwestern UniversityGenome-wide profiling of 5hmC from cfDNA derived from EA and AA patients with MM and its precursors. Genome-wide 5hmC was profiled in patient-derived pla

Updated on:January 22,2024

Targeting RAS proteins may prevent relapse in acute myeloid leukemia

byUniversity of BirminghamAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainRelapses in a common form of leukemia may be preventable following new research that has identified h

Updated on: April 30,2024

Targeting RAS proteins may prevent relapse in acute myeloid leukemia

byUniversity of BirminghamAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainRelapses in a common form of leukemia may be preventable following new research that has identified h

Updated on:April 30,2024

Cancer in adolescent and young adult women before pregnancy does not increase risk for stillborn births, study finds

by Deborah Mann Lake,University of Texas Health Science Center at HoustonCredit: Unsplash/CC0 Public DomainAdolescent and young adult women who were diagnosed with cancer and received chemothera

Updated on: January 23,2024

Cancer in adolescent and young adult women before pregnancy does not increase risk for stillborn births, study finds

by Deborah Mann Lake,University of Texas Health Science Center at HoustonCredit: Unsplash/CC0 Public DomainAdolescent and young adult women who were diagnosed with cancer and received chemothera

Updated on:January 23,2024

Genomic screening can help detect thyroid cancer, finds study

byGeisinger Health SystemCredit: Pixabay/CC0 Public DomainPopulation-based genomic screening can facilitate early detection of medullary thyroid cancer (MTC) in patients with variants in the RET

Updated on: January 23,2024

Genomic screening can help detect thyroid cancer, finds study

byGeisinger Health SystemCredit: Pixabay/CC0 Public DomainPopulation-based genomic screening can facilitate early detection of medullary thyroid cancer (MTC) in patients with variants in the RET

Updated on:January 23,2024

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on: March 30,2024

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on:March 30,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on: February 18,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on:February 18,2024

Neoadjuvant immunotherapy with relatlimab and nivolumab is safe and effective in stage III melanoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainGiving the combination of immune checkpoint inhibitors relatlimab and nivolumab to patients with stage III melanoma bef

Updated on: January 13,2024

Neoadjuvant immunotherapy with relatlimab and nivolumab is safe and effective in stage III melanoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainGiving the combination of immune checkpoint inhibitors relatlimab and nivolumab to patients with stage III melanoma bef

Updated on:January 13,2024

Researchers describe a mechanism inducing self-killing of cancer cells

by The Korea Advanced Institute of Science and Technology (KAIST)Professor Kim (left) and lead author Lee. Credit: The Korea Advanced Institute of Science and Technology (KAIST)Researchers have d

Updated on: June 08,2024

Researchers describe a mechanism inducing self-killing of cancer cells

by The Korea Advanced Institute of Science and Technology (KAIST)Professor Kim (left) and lead author Lee. Credit: The Korea Advanced Institute of Science and Technology (KAIST)Researchers have d

Updated on:June 08,2024

AI in personalized cancer medicine: New therapies require flexible and safe approval conditions

by Viktoria Bosak,Dresden University of TechnologyA perspective on the US and EU regulatory system readiness for AI-enabled personalized drug and cell-based therapies in precision oncology. The

Updated on: March 05,2024

AI in personalized cancer medicine: New therapies require flexible and safe approval conditions

by Viktoria Bosak,Dresden University of TechnologyA perspective on the US and EU regulatory system readiness for AI-enabled personalized drug and cell-based therapies in precision oncology. The

Updated on:March 05,2024