Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on: July 10,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on:July 10,2024

Alzheimer's disease – don't give up on plaque-busting drugs just yet

by Davide Bruno,The ConversationCredit: AI-generated imageAlzheimer's disease is associated with abuild-up of plaquesin the brain called amyloid beta. These plaques are thought t

Updated on: April 02,2024

Alzheimer's disease – don't give up on plaque-busting drugs just yet

by Davide Bruno,The ConversationCredit: AI-generated imageAlzheimer's disease is associated with abuild-up of plaquesin the brain called amyloid beta. These plaques are thought t

Updated on:April 02,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on: April 27,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on:April 27,2024

Faster, stronger … smarter? New research shows the importance of brain training for junior athletes

by Kylie A Steel, Clare MacMahon and Todd Pickering,The ConversationCredit: CC0 Public Domain"Look for the gap!" "Move into space!" "Who's free?"Sound familiar?

Updated on: July 31,2024

Faster, stronger … smarter? New research shows the importance of brain training for junior athletes

by Kylie A Steel, Clare MacMahon and Todd Pickering,The ConversationCredit: CC0 Public Domain"Look for the gap!" "Move into space!" "Who's free?"Sound familiar?

Updated on:July 31,2024

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on: April 02,2024

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on:April 02,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on: April 16,2024

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on:April 16,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on: July 08,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on:July 08,2024

Diminished activation of specific prefrontal brain region may directly contribute to binge eating in bulimia nervosa

by The Mount Sinai HospitalCredit: CC0 Public DomainNew research conducted by an investigator from the Icahn School of Medicine at Mount Sinai has revealed a key neural mechanism underlying the f

Updated on: February 21,2024

Diminished activation of specific prefrontal brain region may directly contribute to binge eating in bulimia nervosa

by The Mount Sinai HospitalCredit: CC0 Public DomainNew research conducted by an investigator from the Icahn School of Medicine at Mount Sinai has revealed a key neural mechanism underlying the f

Updated on:February 21,2024

Sleep your way to better athletic performance

by Dan Lea, Mayo Clinic News NetworkCredit: Unsplash/CC0 Public DomainSleep might not be at the top of the list when you think about ways to boost your athletic performance. But it's just as impor

Updated on: March 05,2024

Sleep your way to better athletic performance

by Dan Lea, Mayo Clinic News NetworkCredit: Unsplash/CC0 Public DomainSleep might not be at the top of the list when you think about ways to boost your athletic performance. But it's just as impor

Updated on:March 05,2024