Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on: March 07,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on:March 07,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

Researchers discover role of microglia during early progression of Alzheimer's disease

by Boston University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have determined how toxic tau fib

Updated on: February 26,2024

Researchers discover role of microglia during early progression of Alzheimer's disease

by Boston University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have determined how toxic tau fib

Updated on:February 26,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on: June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on:June 18,2024

Advances along the gut-liver-brain axis in Alzheimer's disease

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainFour new studies reported at the Alzheimer's Association International Conference (AAIC)

Updated on: April 16,2024

Advances along the gut-liver-brain axis in Alzheimer's disease

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainFour new studies reported at the Alzheimer's Association International Conference (AAIC)

Updated on:April 16,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on: March 30,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on:March 30,2024

New Alzheimer risk gene discovered

by Oxford University PressCredit: CC0 Public DomainA new paper in theJournal of Neuropathology & Experimental Neurologyfinds a gene that may help explain a large part of the genet

Updated on: June 01,2024

New Alzheimer risk gene discovered

by Oxford University PressCredit: CC0 Public DomainA new paper in theJournal of Neuropathology & Experimental Neurologyfinds a gene that may help explain a large part of the genet

Updated on:June 01,2024

Healthy diet may reduce cognitive decline as people age

by Karolinska InstitutetEating healthier may reduce cognitive decline and diminish the negative impact of an unhealthy diet on memory and thinking abilities in older adults, suggests a new study

Updated on: February 26,2024

Healthy diet may reduce cognitive decline as people age

by Karolinska InstitutetEating healthier may reduce cognitive decline and diminish the negative impact of an unhealthy diet on memory and thinking abilities in older adults, suggests a new study

Updated on:February 26,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on: March 09,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on:March 09,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on: February 03,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on:February 03,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on: May 06,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on:May 06,2024