Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

GSA's KAER toolkit promotes care conversations on brain health, cognitive status

by The Gerontological Society of AmericaCredit: Pixabay/CC0 Public DomainThe Gerontological Society of America (GSA) has released a new edition of its KAER toolkit, which is intended to support primar

Updated on: March 30,2024

GSA's KAER toolkit promotes care conversations on brain health, cognitive status

by The Gerontological Society of AmericaCredit: Pixabay/CC0 Public DomainThe Gerontological Society of America (GSA) has released a new edition of its KAER toolkit, which is intended to support primar

Updated on:March 30,2024

GOSH BRC Showcase 2025 - Genomic medicine

Updated on: November 06,2025

GOSH BRC Showcase 2025 - Genomic medicine

Updated on:November 06,2025

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on: March 07,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on:March 07,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on: June 24,2024

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on:June 24,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on: September 06,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on:September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on: September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on:September 06,2024

Intranasal insulin may have pro-cognitive benefits

by Elana GotkineIntranasal insulin (INI) seems to have a beneficial effect on global cognition among patients with Alzheimer's disease (AD)/mild cognitive impairment (MCI), according to a review p

Updated on: March 09,2024

Intranasal insulin may have pro-cognitive benefits

by Elana GotkineIntranasal insulin (INI) seems to have a beneficial effect on global cognition among patients with Alzheimer's disease (AD)/mild cognitive impairment (MCI), according to a review p

Updated on:March 09,2024

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on: April 28,2025

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on:April 28,2025

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024