Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Protecting the brain from dementia-inducing abnormal protein aggregates

by The National Institutes for Quantum Science and TechnologyResearchers from the National Institutes for Quantum Science and Technology prove that the protein p62 eliminates and prevents the formatio

Updated on: April 29,2024

Protecting the brain from dementia-inducing abnormal protein aggregates

by The National Institutes for Quantum Science and TechnologyResearchers from the National Institutes for Quantum Science and Technology prove that the protein p62 eliminates and prevents the formatio

Updated on:April 29,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on: March 05,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on:March 05,2024

Dementia patients' adult kids diagnosed earlier than their parents

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainA person's chance of developing dementia is influenced by family history, variations in certain genes, and

Updated on: May 06,2024

Dementia patients' adult kids diagnosed earlier than their parents

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainA person's chance of developing dementia is influenced by family history, variations in certain genes, and

Updated on:May 06,2024

Study finds cerebrovascular disease to be major determinant of psychosis in patients with Alzheimer's

by St. Michael's HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.About half of all patients with Alzheimer's disease develop symptom

Updated on: February 27,2024

Study finds cerebrovascular disease to be major determinant of psychosis in patients with Alzheimer's

by St. Michael's HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.About half of all patients with Alzheimer's disease develop symptom

Updated on:February 27,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024

Neanderthoids and space brains: Stem cell researcher pushes the boundaries of neuroscience

by Genomic PressAlysson R. Muotri, Ph.D., University of California, San Diego, U.S. Credit:Brain Medicine(2024). https://doi.org/10.61373/bm024k.0082In an interviewpublishedin&

Updated on: October 16,2024

Neanderthoids and space brains: Stem cell researcher pushes the boundaries of neuroscience

by Genomic PressAlysson R. Muotri, Ph.D., University of California, San Diego, U.S. Credit:Brain Medicine(2024). https://doi.org/10.61373/bm024k.0082In an interviewpublishedin&

Updated on:October 16,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on: April 02,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on:April 02,2024

Alzheimer's: Proteomics gives clues toward alternatives to amyloid

by Emory UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In Alzheimer's research, one particular protein looms large: plaque-forming a

Updated on: April 07,2024

Alzheimer's: Proteomics gives clues toward alternatives to amyloid

by Emory UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In Alzheimer's research, one particular protein looms large: plaque-forming a

Updated on:April 07,2024

Autism study reveals pivotal role of neuronal protein CPEB4 condensates

byInstitute for Research in Biomedicine (IRB Barcelona)From left to right: Drs. Mendez, Bartomeu, Salvatella & Garcia Cabau. Credit: IRB BarcelonaAutism is a neurodevelopmental disorder char

Updated on: December 17,2024

Autism study reveals pivotal role of neuronal protein CPEB4 condensates

byInstitute for Research in Biomedicine (IRB Barcelona)From left to right: Drs. Mendez, Bartomeu, Salvatella & Garcia Cabau. Credit: IRB BarcelonaAutism is a neurodevelopmental disorder char

Updated on:December 17,2024