Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on: June 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on:June 01,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on: November 28,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on:November 28,2024

Discovery of macrophages' protective role for nerve damage opens new treatment path

Updated on: March 05,2025

Discovery of macrophages' protective role for nerve damage opens new treatment path

Updated on:March 05,2025

How toxic protein spreads in Alzheimer's disease

by Lund UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Toxic versions of the protein tau are believed to cause death of neurons of the br

Updated on: April 18,2024

How toxic protein spreads in Alzheimer's disease

by Lund UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Toxic versions of the protein tau are believed to cause death of neurons of the br

Updated on:April 18,2024

Brain recordings in people before surgery reveal how minds plan what to say prior to speaking

byNYU Langone HealthCredit: CC0 Public DomainA new study in people undergoing surgery to treat seizures related to epilepsy shows that pauses in speech reveal information about how people's

Updated on: March 28,2024

Brain recordings in people before surgery reveal how minds plan what to say prior to speaking

byNYU Langone HealthCredit: CC0 Public DomainA new study in people undergoing surgery to treat seizures related to epilepsy shows that pauses in speech reveal information about how people's

Updated on:March 28,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on: February 27,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on:February 27,2024

Viral infections including COVID are among the important causes of dementia. One more reason to consider vaccination

by John Donne Potter,The ConversationCredit: Unsplash/CC0 Public DomainWith more of us living into old age than at any other time, dementia is increasing steadily worldwide, with major individua

Updated on: April 29,2024

Viral infections including COVID are among the important causes of dementia. One more reason to consider vaccination

by John Donne Potter,The ConversationCredit: Unsplash/CC0 Public DomainWith more of us living into old age than at any other time, dementia is increasing steadily worldwide, with major individua

Updated on:April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on: April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on:April 29,2024

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on: February 21,2024

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on:February 21,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on: May 06,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on:May 06,2024