Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

Withdrawing dementia drug doubles risk of nursing home placement

by University College LondonWithdrawing a commonly-prescribed Alzheimer's disease drug from people in the advanced stages of the disease doubles their risk of being placed in a nursing home w

Updated on: February 26,2024

Withdrawing dementia drug doubles risk of nursing home placement

by University College LondonWithdrawing a commonly-prescribed Alzheimer's disease drug from people in the advanced stages of the disease doubles their risk of being placed in a nursing home w

Updated on:February 26,2024

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on: April 28,2025

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on:April 28,2025

New figures show only 25% of British adults think dementia risk can be reduced

by Alzheimer's Research UKA leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults thi

Updated on: February 28,2024

New figures show only 25% of British adults think dementia risk can be reduced

by Alzheimer's Research UKA leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults thi

Updated on:February 28,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on: October 21,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on:October 21,2024

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on: March 07,2024

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on:March 07,2024

New study reveals how biological sex influences brain proteins and disease risk

by Emory UniversitySummary of main analyses. Credit:Nature Medicine(2023). DOI:10.1038/s41591-023-02509-yAn Emory led study published inNature MedicineandSynapse&nbs

Updated on: March 02,2024

New study reveals how biological sex influences brain proteins and disease risk

by Emory UniversitySummary of main analyses. Credit:Nature Medicine(2023). DOI:10.1038/s41591-023-02509-yAn Emory led study published inNature MedicineandSynapse&nbs

Updated on:March 02,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on: August 01,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on:August 01,2024

Psychotropic meds tied to risk for post-COVID dementia in seniors

Pre-COVID-19 psychotropic medication use is associated with higher risk for incident dementia following hospitalization for COVID-19 (post-COVID dementia) in older adults, according to a study publish

Updated on: July 04,2024

Psychotropic meds tied to risk for post-COVID dementia in seniors

Pre-COVID-19 psychotropic medication use is associated with higher risk for incident dementia following hospitalization for COVID-19 (post-COVID dementia) in older adults, according to a study publish

Updated on:July 04,2024

Virtual reality app offers unique glimpse into life with dementia

by Alzheimer's Research UKCredit: Alzheimer's Research UKAn innovative virtual reality smartphone app – "A Walk Through Dementia" – will launch at a three-day public installatio

Updated on: March 09,2024

Virtual reality app offers unique glimpse into life with dementia

by Alzheimer's Research UKCredit: Alzheimer's Research UKAn innovative virtual reality smartphone app – "A Walk Through Dementia" – will launch at a three-day public installatio

Updated on:March 09,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

How a tangled protein kills brain cells, promotes Alzheimer's

by Lisa Marshall,University of Colorado at BoulderGraphical abstract. Credit:Neuron(2021). DOI: 10.1016/j.neuron.2021.03.026Look deep inside the brain of someone with Alzheimer's

Updated on: July 04,2024

How a tangled protein kills brain cells, promotes Alzheimer's

by Lisa Marshall,University of Colorado at BoulderGraphical abstract. Credit:Neuron(2021). DOI: 10.1016/j.neuron.2021.03.026Look deep inside the brain of someone with Alzheimer's

Updated on:July 04,2024