Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on: April 29,2024

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on:April 29,2024

Team develops gene therapy to 'pre-treat' neuroblastoma tumors

by Kim Horner,University of Texas at DallasSchematic detailing the experimental procedure and the proposed mechanisms of action of iNOS gene therapy. Credit:Theranostics(2023). DOI:

Updated on: January 02,2024

Team develops gene therapy to 'pre-treat' neuroblastoma tumors

by Kim Horner,University of Texas at DallasSchematic detailing the experimental procedure and the proposed mechanisms of action of iNOS gene therapy. Credit:Theranostics(2023). DOI:

Updated on:January 02,2024

Finding flicker's therapeutic pathway, opening the door to non-invasive treatments for neurodegenerative diseases

by Jerry Grillo,Georgia Institute of TechnologyProposed mechanisms by which 40 Hz flicker changes microglia and cytokine signaling. Credit:Science Advances(2023). DOI: 10.1126/sciadv

Updated on: May 28,2024

Finding flicker's therapeutic pathway, opening the door to non-invasive treatments for neurodegenerative diseases

by Jerry Grillo,Georgia Institute of TechnologyProposed mechanisms by which 40 Hz flicker changes microglia and cytokine signaling. Credit:Science Advances(2023). DOI: 10.1126/sciadv

Updated on:May 28,2024

Older class of type 2 diabetes drugs, glitazones, linked to 22% reduction in dementia risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainUse of an older class of type 2 diabetes drugs called glitazones, also known as thiazolidinediones or TZDs for short, is linked to a 22%

Updated on: June 24,2024

Older class of type 2 diabetes drugs, glitazones, linked to 22% reduction in dementia risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainUse of an older class of type 2 diabetes drugs called glitazones, also known as thiazolidinediones or TZDs for short, is linked to a 22%

Updated on:June 24,2024

Medication may stop migraines before headache starts, study shows

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainWhen taken at the first signs of a migraine, before headache pain begins, a drug called ubrogepant may be effective in helping pe

Updated on: September 06,2024

Medication may stop migraines before headache starts, study shows

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainWhen taken at the first signs of a migraine, before headache pain begins, a drug called ubrogepant may be effective in helping pe

Updated on:September 06,2024

Alzheimer's researchers use physics techniques to investigate iron storage in the brain

byLeiden UniversityCredit: Matthias Zomer/PexelsExactly how Alzheimer's disease develops is not well understood, but an imbalance of iron in the brain might just play a role. Martina Huber o

Updated on: January 06,2024

Alzheimer's researchers use physics techniques to investigate iron storage in the brain

byLeiden UniversityCredit: Matthias Zomer/PexelsExactly how Alzheimer's disease develops is not well understood, but an imbalance of iron in the brain might just play a role. Martina Huber o

Updated on:January 06,2024

Brain's sensitivity to different types of regret may impact mood disorders like depression

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainResearchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regre

Updated on: February 21,2024

Brain's sensitivity to different types of regret may impact mood disorders like depression

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainResearchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regre

Updated on:February 21,2024

New gene therapy for muscular dystrophy offers hope

byUniversity of Washington School of MedicineA schematic illustration of a multi-shuttle system to deliver full dystrophin protein to muscle cells body-wide as a genetic therapy for muscular dys

Updated on: July 25,2024

New gene therapy for muscular dystrophy offers hope

byUniversity of Washington School of MedicineA schematic illustration of a multi-shuttle system to deliver full dystrophin protein to muscle cells body-wide as a genetic therapy for muscular dys

Updated on:July 25,2024

Testing a new radioactive drug to detect Alzheimer's

by Kari Williamson,Norwegian University of Science and TechnologyChemist Jin Han prepares a radioactive patient dose. The glass with the dose is transported in a 14 kg heavy and radiation-proof

Updated on: May 05,2024

Testing a new radioactive drug to detect Alzheimer's

by Kari Williamson,Norwegian University of Science and TechnologyChemist Jin Han prepares a radioactive patient dose. The glass with the dose is transported in a 14 kg heavy and radiation-proof

Updated on:May 05,2024

Researchers determine the structural basis for ApoE-Aβ interactions

by Boston University School of MedicineStructural model of apoE docked onto Aβ1–40fibril from AD vasculature. The model was obtained by using apoE segments shown in supplemental Fig. 2d–h a

Updated on: February 24,2024

Researchers determine the structural basis for ApoE-Aβ interactions

by Boston University School of MedicineStructural model of apoE docked onto Aβ1–40fibril from AD vasculature. The model was obtained by using apoE segments shown in supplemental Fig. 2d–h a

Updated on:February 24,2024

Researchers use pioneering new method to unlock brain's noradrenaline system

byVirginia TechAn international team of researchers led by Virginia Tech scientist Read Montague with the Fralin Biomedical Research Institute at VTC has provided new insight into brain function

Updated on: January 06,2024

Researchers use pioneering new method to unlock brain's noradrenaline system

byVirginia TechAn international team of researchers led by Virginia Tech scientist Read Montague with the Fralin Biomedical Research Institute at VTC has provided new insight into brain function

Updated on:January 06,2024

Very irregular sleep linked to higher risk of dementia

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPeople who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns,

Updated on: February 24,2024

Very irregular sleep linked to higher risk of dementia

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPeople who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns,

Updated on:February 24,2024