Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on: June 05,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on:June 05,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on: May 05,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on:May 05,2024

Stunting in infancy linked to differences in cognitive and brain function

byUniversity of East AngliaCredit: Pixabay/CC0 Public DomainChildren who are too short for their age can suffer reduced cognitive ability arising from differences in brain function as early as s

Updated on: January 12,2024

Stunting in infancy linked to differences in cognitive and brain function

byUniversity of East AngliaCredit: Pixabay/CC0 Public DomainChildren who are too short for their age can suffer reduced cognitive ability arising from differences in brain function as early as s

Updated on:January 12,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on: January 07,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on:January 07,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on: April 27,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on:April 27,2024

Testing effectiveness of a mobile app for assessment of dementia symptoms

by Regenstrief InstituteRegenstrief Institute research scientist Daniel Bateman, M.D. is testing the effectiveness of Brain CareNotes , a novel mobile app for assessment of dementia symptoms. Cre

Updated on: May 05,2024

Testing effectiveness of a mobile app for assessment of dementia symptoms

by Regenstrief InstituteRegenstrief Institute research scientist Daniel Bateman, M.D. is testing the effectiveness of Brain CareNotes , a novel mobile app for assessment of dementia symptoms. Cre

Updated on:May 05,2024

Moral emotions, a diagnotic tool for frontotemporal dementia?

by IOS PressCredit: CC0 Public DomainA study conducted by Marc Teichmann and Carole Azuar at the Brain and Spine Institute in Paris (France) and at the Pitié-Salpêtrière Hospital shows a particul

Updated on: May 20,2024

Moral emotions, a diagnotic tool for frontotemporal dementia?

by IOS PressCredit: CC0 Public DomainA study conducted by Marc Teichmann and Carole Azuar at the Brain and Spine Institute in Paris (France) and at the Pitié-Salpêtrière Hospital shows a particul

Updated on:May 20,2024

Tau protein suppresses neural activity in mouse models of Alzheimer's disease

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainA study from Massachusetts General Hospital (MGH) investigators sheds new light on ho

Updated on: April 02,2024

Tau protein suppresses neural activity in mouse models of Alzheimer's disease

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainA study from Massachusetts General Hospital (MGH) investigators sheds new light on ho

Updated on:April 02,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on: February 21,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on:February 21,2024

Diminished activation of specific prefrontal brain region may directly contribute to binge eating in bulimia nervosa

by The Mount Sinai HospitalCredit: CC0 Public DomainNew research conducted by an investigator from the Icahn School of Medicine at Mount Sinai has revealed a key neural mechanism underlying the f

Updated on: February 21,2024

Diminished activation of specific prefrontal brain region may directly contribute to binge eating in bulimia nervosa

by The Mount Sinai HospitalCredit: CC0 Public DomainNew research conducted by an investigator from the Icahn School of Medicine at Mount Sinai has revealed a key neural mechanism underlying the f

Updated on:February 21,2024

Is the brain wired differently in people with addiction?

by Mylène Tremblay,University of MontrealCredit: Pixabay/CC0 Public DomainSome 10% to 15% of people will have a substance abuse problem at some point in their life, making it one of the most com

Updated on: February 05,2024

Is the brain wired differently in people with addiction?

by Mylène Tremblay,University of MontrealCredit: Pixabay/CC0 Public DomainSome 10% to 15% of people will have a substance abuse problem at some point in their life, making it one of the most com

Updated on:February 05,2024

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on: January 10,2024

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on:January 10,2024