A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on: April 06,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on:April 06,2024

Clustering method can better describe the pathological process in patients with traumatic brain injury

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainMonitoring brain injury biomarkers and glucose variation in patients who have suffered an acute cranial injury during the entire first wee

Updated on: January 10,2024

Clustering method can better describe the pathological process in patients with traumatic brain injury

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainMonitoring brain injury biomarkers and glucose variation in patients who have suffered an acute cranial injury during the entire first wee

Updated on:January 10,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on: June 01,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on:June 01,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on: February 24,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on:February 24,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on: April 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on:April 02,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024

Touching a nerve in the fight against chronic pain and diseases

JANUARY 11, 2024by Vittoria D'Alessio,Horizon: The EU Research & Innovation MagazineCredit: Pixabay/CC0 Public DomainThe human body's longest cranial nerve has the potential to impro

Updated on: March 13,2024

Touching a nerve in the fight against chronic pain and diseases

JANUARY 11, 2024by Vittoria D'Alessio,Horizon: The EU Research & Innovation MagazineCredit: Pixabay/CC0 Public DomainThe human body's longest cranial nerve has the potential to impro

Updated on:March 13,2024

Small brains can accomplish big things, according to new theoretical research

Small brains can accomplish big things, according to new theoretical researchbyHoward Hughes Medical InstituteA biological attractor network overcomes hypothesized limitations of discreteness. C

Updated on: October 18,2024

Small brains can accomplish big things, according to new theoretical research

Small brains can accomplish big things, according to new theoretical researchbyHoward Hughes Medical InstituteA biological attractor network overcomes hypothesized limitations of discreteness. C

Updated on:October 18,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024