Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Study looks at whether daily limb compressions reduce dementia

by Medical College of GeorgiaDr. David Hess is Chairman of the Department of Neurology at the Medical College of Georgia at Georgia Regents University. Credit: Phil JonesA new study is looking at

Updated on: February 26,2024

Study looks at whether daily limb compressions reduce dementia

by Medical College of GeorgiaDr. David Hess is Chairman of the Department of Neurology at the Medical College of Georgia at Georgia Regents University. Credit: Phil JonesA new study is looking at

Updated on:February 26,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on: August 08,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on:August 08,2024

Neuronal diversity impacts the brain's information processing

by Melissa Rohman,Northwestern UniversitySpike threshold heterogeneity affects the function generation properties of spiking neural networks. (A) Reservoir computing architecture used for functi

Updated on: March 13,2024

Neuronal diversity impacts the brain's information processing

by Melissa Rohman,Northwestern UniversitySpike threshold heterogeneity affects the function generation properties of spiking neural networks. (A) Reservoir computing architecture used for functi

Updated on:March 13,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on: February 03,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on:February 03,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on: May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on:May 18,2024

High rate of diabetes, high blood pressure in Puerto Ricans linked to brain changes

by American Academy of NeurologyCredit: CC0 Public DomainThe high rate of diabetes and high blood pressure combined in Puerto Rican people may be linked to structural changes in the brain, accord

Updated on: February 05,2024

High rate of diabetes, high blood pressure in Puerto Ricans linked to brain changes

by American Academy of NeurologyCredit: CC0 Public DomainThe high rate of diabetes and high blood pressure combined in Puerto Rican people may be linked to structural changes in the brain, accord

Updated on:February 05,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on: January 12,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on:January 12,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024