ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on: June 14,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on:June 14,2024

Gene ID'd as potential therapeutic target for dementia in Parkinson's

by Washington University School of MedicineClumps of the Parkinson's protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington Univer

Updated on: June 14,2024

Gene ID'd as potential therapeutic target for dementia in Parkinson's

by Washington University School of MedicineClumps of the Parkinson's protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington Univer

Updated on:June 14,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on: June 14,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on:June 14,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on: June 14,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on:June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on: June 14,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on:June 14,2024

Socially active 60-year-olds face lower dementia risk

by University College LondonCredit: CC0 Public DomainBeing more socially active in your 50s and 60s predicts a lower risk of developing dementia later on, finds a new UCL-led study.Thelongi

Updated on: June 14,2024

Socially active 60-year-olds face lower dementia risk

by University College LondonCredit: CC0 Public DomainBeing more socially active in your 50s and 60s predicts a lower risk of developing dementia later on, finds a new UCL-led study.Thelongi

Updated on:June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

Genetic changes implicated in altered Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainToday, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is

Updated on: June 14,2024

Genetic changes implicated in altered Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainToday, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is

Updated on:June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024

Machine-learning algorithms used to detect Alzheimer's during phone conversations

by Bob Yirka , Medical XpressThe whole process in the present study. Credit: Shimoda et al, 2021 (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers working at the Department of Public Health

Updated on: June 14,2024

Machine-learning algorithms used to detect Alzheimer's during phone conversations

by Bob Yirka , Medical XpressThe whole process in the present study. Credit: Shimoda et al, 2021 (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers working at the Department of Public Health

Updated on:June 14,2024

Gene yields insights into the causes of neurodegeneration

by Cornell UniversityCredit: CC0 Public DomainAcross the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal

Updated on: June 14,2024

Gene yields insights into the causes of neurodegeneration

by Cornell UniversityCredit: CC0 Public DomainAcross the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal

Updated on:June 14,2024