Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on: April 22,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on:April 22,2024

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on: June 20,2024

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on:June 20,2024

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on: May 29,2024

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on:May 29,2024

Quality of cartilage repair tissue can also be determined without a surgery

by Medical University of ViennaA team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has

Updated on: March 24,2024

Quality of cartilage repair tissue can also be determined without a surgery

by Medical University of ViennaA team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has

Updated on:March 24,2024

β-damascone: Using the aroma component of rose fragrance as a novel immunomodulator

by Tokyo University of ScienceOveractivation of dendritic cells (DCs), components of the immune system, can cause immune diseases. β-damascone, a constituent of rose fragrance was identified as a

Updated on: May 07,2024

β-damascone: Using the aroma component of rose fragrance as a novel immunomodulator

by Tokyo University of ScienceOveractivation of dendritic cells (DCs), components of the immune system, can cause immune diseases. β-damascone, a constituent of rose fragrance was identified as a

Updated on:May 07,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on: March 26,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on:March 26,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on: July 11,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on:July 11,2024

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on: April 20,2024

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on:April 20,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on: April 24,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on:April 24,2024

Rituximab retreatment at clinical relapse cost-effective in RA

(HealthDay)—Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis (RA), according to a study published in the July is

Updated on: April 08,2024

Rituximab retreatment at clinical relapse cost-effective in RA

(HealthDay)—Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis (RA), according to a study published in the July is

Updated on:April 08,2024