New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on: March 26,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on:March 26,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on: March 24,2024

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on:March 24,2024

How much of a boost do 'booster' COVID-19 jabs give?

by King's College LondonCredit: Pixabay/CC0 Public DomainScientists have found the "booster" COVID-19 vaccine program led to a large boost in the antibodies that help protect agains

Updated on: March 13,2024

How much of a boost do 'booster' COVID-19 jabs give?

by King's College LondonCredit: Pixabay/CC0 Public DomainScientists have found the "booster" COVID-19 vaccine program led to a large boost in the antibodies that help protect agains

Updated on:March 13,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on: April 10,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on:April 10,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on: March 19,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on:March 19,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on: May 08,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on:May 08,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on: April 07,2024

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on:April 07,2024

Early RA treatment important for long-term outcomes

(HealthDay)—Early treatment of rheumatoid arthritis (RA) is important for long-term outcomes, and there has been a decrease in mortality rates attributable to RA, according to two studies published on

Updated on: March 28,2024

Early RA treatment important for long-term outcomes

(HealthDay)—Early treatment of rheumatoid arthritis (RA) is important for long-term outcomes, and there has been a decrease in mortality rates attributable to RA, according to two studies published on

Updated on:March 28,2024