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Hematology&Oncology
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Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from
Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

by Elizabeth Chapin,University of KentuckyFong with members of his lab. Credit: University of KentuckyA University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

by Elizabeth Chapin,University of KentuckyFong with members of his lab. Credit: University of KentuckyA University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their
RNA-based molecule enhances therapies against pancreatic cancer

RNA-based molecule enhances therapies against pancreatic cancer

byItalian Institute of TechnologyThe small ring-like structures visible in the magnified area represent the RAD51 protein, which has adopted a non-functional shape as a result of its interaction with

RNA-based molecule enhances therapies against pancreatic cancer

byItalian Institute of TechnologyThe small ring-like structures visible in the magnified area represent the RAD51 protein, which has adopted a non-functional shape as a result of its interaction with
Promising drug can inhibit aggressive breast cancer

Promising drug can inhibit aggressive breast cancer

by Erik Robinson,Oregon Health & Science UniversityGraphical abstract. Credit:Cell Reports Medicine(2025). DOI: 10.1016/j.xcrm.2025.102451New research reveals a drug developed by scientists at Ore

Promising drug can inhibit aggressive breast cancer

by Erik Robinson,Oregon Health & Science UniversityGraphical abstract. Credit:Cell Reports Medicine(2025). DOI: 10.1016/j.xcrm.2025.102451New research reveals a drug developed by scientists at Ore
Subtyping colorectal cancer may improve patient outcome predictions

Subtyping colorectal cancer may improve patient outcome predictions

byKyoto UniversityAn example usage of General Colorectal Cancer Signature (GCS). Credit: KyotoU / Makoto TaketoColorectal cancer, or CRC, is the world's second most lethal cancer based on the numb

Subtyping colorectal cancer may improve patient outcome predictions

byKyoto UniversityAn example usage of General Colorectal Cancer Signature (GCS). Credit: KyotoU / Makoto TaketoColorectal cancer, or CRC, is the world's second most lethal cancer based on the numb
Supportive cancer care: Most patients say human touch outshines tech

Supportive cancer care: Most patients say human touch outshines tech

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew researchpublishedin the November 2025 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkexplores the percep

Supportive cancer care: Most patients say human touch outshines tech

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew researchpublishedin the November 2025 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkexplores the percep
Discovery of pancreatic tumor vulnerability could pave the way for new treatments

Discovery of pancreatic tumor vulnerability could pave the way for new treatments

by Evelyne Dufresne,McGill UniversityCredit:Molecular Cancer(2026). DOI: 10.1186/s12943-026-02587-9A team from the Research Institute of the McGill University Health Center (The Institute), led by Jea

Discovery of pancreatic tumor vulnerability could pave the way for new treatments

by Evelyne Dufresne,McGill UniversityCredit:Molecular Cancer(2026). DOI: 10.1186/s12943-026-02587-9A team from the Research Institute of the McGill University Health Center (The Institute), led by Jea
Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceWhole body lean mass, which is an indicator of muscle mass, increased in the exercise group, while it decreased in the control group. Credit: Anne M

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceWhole body lean mass, which is an indicator of muscle mass, increased in the exercise group, while it decreased in the control group. Credit: Anne M
New analytical method reveals how drug combinations act in leukemia

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r
PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

byRadboud UniversityNuclear medicine physician James Nagarajah from Radboudumc in the clinics. Credit: RadboudumcWhere previous research showed that PSMA therapy for prostate cancer can prolong the li

PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

byRadboud UniversityNuclear medicine physician James Nagarajah from Radboudumc in the clinics. Credit: RadboudumcWhere previous research showed that PSMA therapy for prostate cancer can prolong the li
Why some cancer therapies don't work for all patients: A tumor backup survival pathway

Why some cancer therapies don't work for all patients: A tumor backup survival pathway

by Anne Trafton,Massachusetts Institute of TechnologyMany of the targeted tumors turn on a backup survival pathway that helps them keep growing when tyrosine kinase—pictured here as strands—is turned

Why some cancer therapies don't work for all patients: A tumor backup survival pathway

by Anne Trafton,Massachusetts Institute of TechnologyMany of the targeted tumors turn on a backup survival pathway that helps them keep growing when tyrosine kinase—pictured here as strands—is turned
Researchers demonstrate breakthroughs in cancer treatment quality through AI-enhanced data analytics

Researchers demonstrate breakthroughs in cancer treatment quality through AI-enhanced data analytics

byUniversity of Tennessee at KnoxvilleSpatial clusters of the top six county-level features influencing LC mortality predictions using Getis-ord Gi. Credit:JCO Clinical Cancer Informatics(2025). DOI:

Researchers demonstrate breakthroughs in cancer treatment quality through AI-enhanced data analytics

byUniversity of Tennessee at KnoxvilleSpatial clusters of the top six county-level features influencing LC mortality predictions using Getis-ord Gi. Credit:JCO Clinical Cancer Informatics(2025). DOI: