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Hematology&Oncology
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Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation

Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation

byHarvard UniversityThe personalized biomaterial-based cancer vaccine consists of a porous biomaterial scaffold the size of an aspirin tablet that is infused with immune cell-recruiting and activating

Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation

byHarvard UniversityThe personalized biomaterial-based cancer vaccine consists of a porous biomaterial scaffold the size of an aspirin tablet that is infused with immune cell-recruiting and activating
30-year smoking duration-based criteria could increase lung cancer screening

30-year smoking duration-based criteria could increase lung cancer screening

by Elana GotkineThirty-year smoking duration-based criteria could reduce eligibility gaps for all races relative to whites, while improving six-year lung cancer detection sensitivity, according to a s

30-year smoking duration-based criteria could increase lung cancer screening

by Elana GotkineThirty-year smoking duration-based criteria could reduce eligibility gaps for all races relative to whites, while improving six-year lung cancer detection sensitivity, according to a s
Accelerated cancer drug approvals yield modest survival gains at significant Medicare cost

Accelerated cancer drug approvals yield modest survival gains at significant Medicare cost

byHarvard Pilgrim Health Care InstituteCredit: Unsplash/CC0 Public DomainEarly access to new cancer drugs, granted accelerated approval by the U.S. Food and Drug Administration (FDA), has provided mix

Accelerated cancer drug approvals yield modest survival gains at significant Medicare cost

byHarvard Pilgrim Health Care InstituteCredit: Unsplash/CC0 Public DomainEarly access to new cancer drugs, granted accelerated approval by the U.S. Food and Drug Administration (FDA), has provided mix
Blood test can detect single lung cancer calls using infrared technique

Blood test can detect single lung cancer calls using infrared technique

by Meg Cox,Loughborough UniversityThis figure shows how the technique identifies a single circulating tumor cell (CTC) in a lung cancer patient's blood sample. The sample is first viewed under a m

Blood test can detect single lung cancer calls using infrared technique

by Meg Cox,Loughborough UniversityThis figure shows how the technique identifies a single circulating tumor cell (CTC) in a lung cancer patient's blood sample. The sample is first viewed under a m
Black patients diagnosed with aggressive leukemia experience worse outcomes

Black patients diagnosed with aggressive leukemia experience worse outcomes

byUniversity of Maryland School of MedicineCredit: Ninthgrid from PexelsCompared with white patients, Black patients with an aggressive form of leukemia—called acute myeloid leukemia (AML)—were on ave

Black patients diagnosed with aggressive leukemia experience worse outcomes

byUniversity of Maryland School of MedicineCredit: Ninthgrid from PexelsCompared with white patients, Black patients with an aggressive form of leukemia—called acute myeloid leukemia (AML)—were on ave
Combination therapy shows potential to treat pediatric brain cancer ATRT

Combination therapy shows potential to treat pediatric brain cancer ATRT

bySt. Jude Children's Research HospitalAs published inNeuro-Oncology Pediatrics, a combination therapy may offer a new treatment strategy for atypical teratoid rhabdoid tumor (ATRT), a rare pediat

Combination therapy shows potential to treat pediatric brain cancer ATRT

bySt. Jude Children's Research HospitalAs published inNeuro-Oncology Pediatrics, a combination therapy may offer a new treatment strategy for atypical teratoid rhabdoid tumor (ATRT), a rare pediat
Cause or effect? Study answers question about gene linked with colorectal cancer

Cause or effect? Study answers question about gene linked with colorectal cancer

by Jacqueline Mitchell,Harvard Medical SchoolIn mice lacking the COSMC gene, gut cells underwent vast changes in appearance and gene activity that predisposed them to develop into colorectal cancer. H

Cause or effect? Study answers question about gene linked with colorectal cancer

by Jacqueline Mitchell,Harvard Medical SchoolIn mice lacking the COSMC gene, gut cells underwent vast changes in appearance and gene activity that predisposed them to develop into colorectal cancer. H
Nanovaccine shows great promise for treating HPV-related cancers

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit
Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme's role

Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme's role

byInstitute of Organic Chemistry and Biochemistry of the CASModel of alcohol metabolism leading to acetaldehyde interstrand crosslink (AA-ICL). Credit:Communications Biology(2025). DOI: 10.1038/s42003

Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme's role

byInstitute of Organic Chemistry and Biochemistry of the CASModel of alcohol metabolism leading to acetaldehyde interstrand crosslink (AA-ICL). Credit:Communications Biology(2025). DOI: 10.1038/s42003
Blood analysis shows whether brain cancer treatment is working

Blood analysis shows whether brain cancer treatment is working

by Kate McAlpine,University of MichiganDesign and validation ofGlioExoChip using EVPs from GBM cell lines. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65681-4The effectiveness of chemo

Blood analysis shows whether brain cancer treatment is working

by Kate McAlpine,University of MichiganDesign and validation ofGlioExoChip using EVPs from GBM cell lines. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65681-4The effectiveness of chemo
Cancer messenger substances disrupt muscle function and trigger muscle breakdown

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l
Factoring in frailty and age could improve pancreatic cancer treatment

Factoring in frailty and age could improve pancreatic cancer treatment

bySanford-Burnham PrebysAging accelerates tumor progression in a syngeneic orthotopic PDAC mouse model. Credit:Cancer Research(2025). DOI: 10.1158/0008-5472.can-25-1904While some risk factors for canc

Factoring in frailty and age could improve pancreatic cancer treatment

bySanford-Burnham PrebysAging accelerates tumor progression in a syngeneic orthotopic PDAC mouse model. Credit:Cancer Research(2025). DOI: 10.1158/0008-5472.can-25-1904While some risk factors for canc