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Hematology&Oncology
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Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP
Microscopic cell changes linked to cancer's rapid growth in stiff tissues

Microscopic cell changes linked to cancer's rapid growth in stiff tissues

by Bailey Noah,Texas A&M UniversityResearchers in the Lele Lab analyzing cell imaging data. Credit: Texas A&M EngineeringIn 2022 alone, over 20 million people were diagnosed with cancer,

Microscopic cell changes linked to cancer's rapid growth in stiff tissues

by Bailey Noah,Texas A&M UniversityResearchers in the Lele Lab analyzing cell imaging data. Credit: Texas A&M EngineeringIn 2022 alone, over 20 million people were diagnosed with cancer,
Proof-of-concept study bioengineers therapeutics for improved cancer treatment

Proof-of-concept study bioengineers therapeutics for improved cancer treatment

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainA team of Children's Medical Research Institute (CMRI) scientists has identified a new method for producing a therapeut

Proof-of-concept study bioengineers therapeutics for improved cancer treatment

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainA team of Children's Medical Research Institute (CMRI) scientists has identified a new method for producing a therapeut
New treatment target for neuroendocrine prostate cancer discovered

New treatment target for neuroendocrine prostate cancer discovered

by Roswell Park Comprehensive Cancer CenterMitochondria are dysfunctional in neuroendocrine prostate tumors. Credit:Oncogene(2024). DOI: 10.1038/s41388-024-03261-4A team of researchers at

New treatment target for neuroendocrine prostate cancer discovered

by Roswell Park Comprehensive Cancer CenterMitochondria are dysfunctional in neuroendocrine prostate tumors. Credit:Oncogene(2024). DOI: 10.1038/s41388-024-03261-4A team of researchers at
Changes in blood cell production over the lifetime could impact leukemia outcomes

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x
PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

by Elana GotkineAmong patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence

PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

by Elana GotkineAmong patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence
Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

byChinese Academy of SciencesMouse craniopharyngioma. Credit: IGDBChinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treat

Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

byChinese Academy of SciencesMouse craniopharyngioma. Credit: IGDBChinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treat
Overcoming glioblastoma resistance to chemotherapy

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &
Cancer risk declines in old age: New research helps explain why

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415