Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

New Crohn's disease scoring method improves monitoring among adults and kids

by Cecilia Warchol,University of MichiganHigh magnification micrograph of Crohn's disease. Biopsy of esophagus. H&E stain. Credit: Nephron/WikipediaFor many years, the Simple Endoscopic

Updated on: May 06,2024

New Crohn's disease scoring method improves monitoring among adults and kids

by Cecilia Warchol,University of MichiganHigh magnification micrograph of Crohn's disease. Biopsy of esophagus. H&E stain. Credit: Nephron/WikipediaFor many years, the Simple Endoscopic

Updated on:May 06,2024

COVID-19: Enzyme targeted by virus also influences gut inflammation

by Cedars-Sinai Medical CenterThe novel coronavirus as seen under a microscope. Credit: Courtesy of the National Institutes of Health.An enzyme that helps COVID-19 (coronavirus) infect the body a

Updated on: February 21,2024

COVID-19: Enzyme targeted by virus also influences gut inflammation

by Cedars-Sinai Medical CenterThe novel coronavirus as seen under a microscope. Credit: Courtesy of the National Institutes of Health.An enzyme that helps COVID-19 (coronavirus) infect the body a

Updated on:February 21,2024

Age and aging have critical effects on the gut microbiome

by Cedars-Sinai Medical CenterA new study led by Ruchi Mathur, MD, found that aging produces significant changes in the microbiome of the human small intestine. Credit: Cedars-SinaiResearchers at

Updated on: May 28,2024

Age and aging have critical effects on the gut microbiome

by Cedars-Sinai Medical CenterA new study led by Ruchi Mathur, MD, found that aging produces significant changes in the microbiome of the human small intestine. Credit: Cedars-SinaiResearchers at

Updated on:May 28,2024

Research shows stimulating tuft cell production reverses intestinal inflammation

by Marissa Shapiro,Vanderbilt UniversityRestoration of the finger-like architecture of the intestine upon tuft cell stimulation in Crohn’s disease model (left) untreated, (right) treated. Arrows

Updated on: April 20,2024

Research shows stimulating tuft cell production reverses intestinal inflammation

by Marissa Shapiro,Vanderbilt UniversityRestoration of the finger-like architecture of the intestine upon tuft cell stimulation in Crohn’s disease model (left) untreated, (right) treated. Arrows

Updated on:April 20,2024

Study reveals colon tumor location matters for metastatic disease

by Yale Cancer Center/Smilow Cancer HospitalHuman anatomy of the gastrointestinal (GI) system; the GI system is divided in stomach, small and large intestines; the large intestine (colon) is subdivide

Updated on: April 03,2024

Study reveals colon tumor location matters for metastatic disease

by Yale Cancer Center/Smilow Cancer HospitalHuman anatomy of the gastrointestinal (GI) system; the GI system is divided in stomach, small and large intestines; the large intestine (colon) is subdivide

Updated on:April 03,2024

Researchers fast-track app for bowel disease sufferers in new COVID-19 era

by University of OtagoCredit: CC0 Public DomainThe COVID-19 pandemic has resulted in University of Otago researchers, in collaboration with others in New Zealand, fast-tracking development of a s

Updated on: April 03,2024

Researchers fast-track app for bowel disease sufferers in new COVID-19 era

by University of OtagoCredit: CC0 Public DomainThe COVID-19 pandemic has resulted in University of Otago researchers, in collaboration with others in New Zealand, fast-tracking development of a s

Updated on:April 03,2024

Human norovirus GII.4 exploits unexpected entry mechanism to cause gastroenteritis

by Baylor College of MedicineGII.4 capsid protein elicits acidification and endocytosis in HIEs.aViral replication at 24 h (black dots) compared to bound virus at 1 h (blue dots) and

Updated on: May 26,2024

Human norovirus GII.4 exploits unexpected entry mechanism to cause gastroenteritis

by Baylor College of MedicineGII.4 capsid protein elicits acidification and endocytosis in HIEs.aViral replication at 24 h (black dots) compared to bound virus at 1 h (blue dots) and

Updated on:May 26,2024

Diagnosing pediatric Crohn disease with radiomic and clinical data

by American Roentgen Ray SocietyAxial T2-weighted SSFSE images show greatest terminal thickness—without (top) and with (bottom) four ROI segmentations. (Green = whole-bowel ROI; yellow = bowel-co

Updated on: March 28,2024

Diagnosing pediatric Crohn disease with radiomic and clinical data

by American Roentgen Ray SocietyAxial T2-weighted SSFSE images show greatest terminal thickness—without (top) and with (bottom) four ROI segmentations. (Green = whole-bowel ROI; yellow = bowel-co

Updated on:March 28,2024

A novel targeted molecular therapy for drug-resistant biliary tract cancer

A novel targeted molecular therapy for drug-resistant biliary tract cancerbyOkayama UniversityWhen human biliary tract cancer cells are transfected with miR-451a, cell proliferation within the c

Updated on: January 24,2024

A novel targeted molecular therapy for drug-resistant biliary tract cancer

A novel targeted molecular therapy for drug-resistant biliary tract cancerbyOkayama UniversityWhen human biliary tract cancer cells are transfected with miR-451a, cell proliferation within the c

Updated on:January 24,2024

Revisional-RYGB examined for GERD and weight-loss failure

by Elana GotkineFollowing sleeve gastrectomy (SG), revisional Roux-Y-gastric-bypass (RYGB) is beneficial for remission of reflux symptoms and extra weight loss, according to a study published online A

Updated on: April 24,2024

Revisional-RYGB examined for GERD and weight-loss failure

by Elana GotkineFollowing sleeve gastrectomy (SG), revisional Roux-Y-gastric-bypass (RYGB) is beneficial for remission of reflux symptoms and extra weight loss, according to a study published online A

Updated on:April 24,2024

Multiple tumors without kinship occur simultaneously in the small intestine in neuroendocrine cancer

by University of GothenburgFig. 1: Whole genome sequencing of 11 primary tumors and metastases from a single SI-NET patient supports independent clonal evolution. a Section of the small intestine

Updated on: May 23,2024

Multiple tumors without kinship occur simultaneously in the small intestine in neuroendocrine cancer

by University of GothenburgFig. 1: Whole genome sequencing of 11 primary tumors and metastases from a single SI-NET patient supports independent clonal evolution. a Section of the small intestine

Updated on:May 23,2024