Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Updated on: March 14,2024

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Updated on:March 14,2024

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.

Updated on: July 05,2024

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.

Updated on:July 05,2024

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Updated on: March 30,2024

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Updated on:March 30,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on: March 30,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on:March 30,2024

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Updated on: March 30,2024

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Updated on:March 30,2024

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Updated on: March 13,2024

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Updated on:March 13,2024

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Updated on: March 14,2024

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Updated on:March 14,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on: March 13,2024

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on:March 13,2024

Social isolation, loneliness and frailty in older adults have a complex and sometimes mutually reinforcing relationship

Social isolation, loneliness and frailty in older adults have a complex and sometimes mutually reinforcing relationshipby Patrick Lejtenyi,Concordia UniversityCredit: Matt Barnard from PexelsA n

Updated on: December 04,2024

Social isolation, loneliness and frailty in older adults have a complex and sometimes mutually reinforcing relationship

Social isolation, loneliness and frailty in older adults have a complex and sometimes mutually reinforcing relationshipby Patrick Lejtenyi,Concordia UniversityCredit: Matt Barnard from PexelsA n

Updated on:December 04,2024

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on: March 14,2024

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on:March 14,2024

Investigating the ethical landscape of brain organoid research

FEBRUARY 28, 2024byKyoto UniversityCredit: Pixabay/CC0 Public DomainWith advances in neuroscience and the development of new technologies, new ethical considerations have emerged. This is partic

Updated on: March 25,2024

Investigating the ethical landscape of brain organoid research

FEBRUARY 28, 2024byKyoto UniversityCredit: Pixabay/CC0 Public DomainWith advances in neuroscience and the development of new technologies, new ethical considerations have emerged. This is partic

Updated on:March 25,2024