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Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there
Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

byLudwig Maximilian University of MunichSchematic of the experimental design; PBMCs, peripheral blood mononuclear cells. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01656

Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

byLudwig Maximilian University of MunichSchematic of the experimental design; PBMCs, peripheral blood mononuclear cells. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01656
Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02
Key mechanisms identified for regeneration of neurons

Key mechanisms identified for regeneration of neurons

byLudwig Maximilian University of MunichCredit: Pixabay/CC0 Public DomainNeurological disorders, such as trauma, stroke, epilepsy, and various neurodegenerative diseases, often lead to the perma

Key mechanisms identified for regeneration of neurons

byLudwig Maximilian University of MunichCredit: Pixabay/CC0 Public DomainNeurological disorders, such as trauma, stroke, epilepsy, and various neurodegenerative diseases, often lead to the perma
Off-label use of a common antibiotic to treat muscular dystrophy

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads
Study finds moderately elevated fracture risk following use of sedative–hypnotics

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff
New study sheds light on how our brains perceive—or fail to perceive—what we see

New study sheds light on how our brains perceive—or fail to perceive—what we see

byAllen Institute for Brain ScienceCredit: Magoi from PexelsA newstudyinNature Neuroscienceon 'visual masking' sheds light on how we 'unsee' things and po

New study sheds light on how our brains perceive—or fail to perceive—what we see

byAllen Institute for Brain ScienceCredit: Magoi from PexelsA newstudyinNature Neuroscienceon 'visual masking' sheds light on how we 'unsee' things and po
Emerging trends and challenges in the grouping of digital health technologies

Emerging trends and challenges in the grouping of digital health technologies

byiCube ProgrammeCredit: Natanael Melchor on UnsplashThe widespread adoption of Digital Health Technologies (DHTs) is now evolving, with a growing trend towards the integration of these technolo

Emerging trends and challenges in the grouping of digital health technologies

byiCube ProgrammeCredit: Natanael Melchor on UnsplashThe widespread adoption of Digital Health Technologies (DHTs) is now evolving, with a growing trend towards the integration of these technolo
The roles of genes and 3D genome folds in determining health

The roles of genes and 3D genome folds in determining health

by Carmen Rotte,Max Planck SocietyModel for the mechanism of chromatin domain formation in S. cerevisiae. Credit:Nature Genetics(2024). DOI:10.1038/s41588-023-01649-8Whether we stay

The roles of genes and 3D genome folds in determining health

by Carmen Rotte,Max Planck SocietyModel for the mechanism of chromatin domain formation in S. cerevisiae. Credit:Nature Genetics(2024). DOI:10.1038/s41588-023-01649-8Whether we stay
Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th