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Breakthroughs
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Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl
Study: Solid organ transplant patients benefit from COVID-19 treatment

Study: Solid organ transplant patients benefit from COVID-19 treatment

byCedars-Sinai Medical CenterTix-Cil dosing and infections during the study period. The frequency and timing of Tix-Cil dosing and SARS-CoV-2 infections occurring in the study cohort is shown in

Study: Solid organ transplant patients benefit from COVID-19 treatment

byCedars-Sinai Medical CenterTix-Cil dosing and infections during the study period. The frequency and timing of Tix-Cil dosing and SARS-CoV-2 infections occurring in the study cohort is shown in
How transcription factors influence insulin-producing beta cells

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th
UK issues guidelines for use of stem cell-based embryo models in research

UK issues guidelines for use of stem cell-based embryo models in research

byUniversity of CambridgeThese models can be created in the lab and mimic aspects of early human embryo development, which raises various ethical considerations. Credit: Irene Zorzan and Teresa

UK issues guidelines for use of stem cell-based embryo models in research

byUniversity of CambridgeThese models can be created in the lab and mimic aspects of early human embryo development, which raises various ethical considerations. Credit: Irene Zorzan and Teresa
Precursor of cholesterol protects cells from ferroptosis, study finds

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann
Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod
Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of
Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb
Study eases concern at antipsychotics use in pregnancy

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o
Anti-obesity medications may affect survival in people with knee or hip osteoarthritis

Anti-obesity medications may affect survival in people with knee or hip osteoarthritis

byWileyCredit: Pixabay/CC0 Public DomainNew researchpublishedinArthritis & Rheumatologysuggests that for people overweight or with obesity who also have knee or hip o

Anti-obesity medications may affect survival in people with knee or hip osteoarthritis

byWileyCredit: Pixabay/CC0 Public DomainNew researchpublishedinArthritis & Rheumatologysuggests that for people overweight or with obesity who also have knee or hip o
Researchers roll out a more accurate way to estimate genetic risks of disease

Researchers roll out a more accurate way to estimate genetic risks of disease

by Claire Hendershot,Broad Institute of MIT and HarvardPrediction accuracy and improvement across various types of traits in the European and South Asian ancestry. Credit:Cell Genomics&nbs

Researchers roll out a more accurate way to estimate genetic risks of disease

by Claire Hendershot,Broad Institute of MIT and HarvardPrediction accuracy and improvement across various types of traits in the European and South Asian ancestry. Credit:Cell Genomics&nbs
Research finds peer support vital for those taking medication for severe mental illness

Research finds peer support vital for those taking medication for severe mental illness

byAston UniversityCredit: Pixabay/CC0 Public DomainResearchers at Aston Pharmacy School have found that people with severe mental illness could benefit from peer support to help them manage thei

Research finds peer support vital for those taking medication for severe mental illness

byAston UniversityCredit: Pixabay/CC0 Public DomainResearchers at Aston Pharmacy School have found that people with severe mental illness could benefit from peer support to help them manage thei