Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

by AudioCure Pharma GmbHThe effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the cochlea. (B) Quantification of OHCs 14 d after noise exposure reveal

Updated on: April 06,2024

Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

by AudioCure Pharma GmbHThe effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the cochlea. (B) Quantification of OHCs 14 d after noise exposure reveal

Updated on:April 06,2024

New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

by Isabella Backman,Yale UniversityThe lab of Choukri Ben Mamoun, PhD (left), has a long-standing interest in fighting this tick-borne disease. Credit: Yale UniversityDrug-resistant babesiosis m

Updated on: January 26,2024

New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

by Isabella Backman,Yale UniversityThe lab of Choukri Ben Mamoun, PhD (left), has a long-standing interest in fighting this tick-borne disease. Credit: Yale UniversityDrug-resistant babesiosis m

Updated on:January 26,2024

Diabetes and weight-loss drugs—Ozempic and Wegovy—not associated with increased suicidal thoughts, finds study

byCase Western Reserve UniversityCredit: Unsplash/CC0 Public DomainA new study by researchers at the Case Western Reserve School of Medicine reveals that a chemical used in the diabetes drug Oze

Updated on: January 26,2024

Diabetes and weight-loss drugs—Ozempic and Wegovy—not associated with increased suicidal thoughts, finds study

byCase Western Reserve UniversityCredit: Unsplash/CC0 Public DomainA new study by researchers at the Case Western Reserve School of Medicine reveals that a chemical used in the diabetes drug Oze

Updated on:January 26,2024

New technique reveals earliest signs of genetic mutations

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these chan

Updated on: June 15,2024

New technique reveals earliest signs of genetic mutations

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these chan

Updated on:June 15,2024

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on: March 28,2024

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on:March 28,2024

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c

Updated on: April 28,2024

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c

Updated on:April 28,2024

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Updated on: January 26,2024

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Updated on:January 26,2024

Study finds AI can develop treatments to prevent 'superbugs'

byCleveland ClinicSchematic evolutionary simulation and tested optimization approaches. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073/pnas.2303165121Clev

Updated on: April 28,2024

Study finds AI can develop treatments to prevent 'superbugs'

byCleveland ClinicSchematic evolutionary simulation and tested optimization approaches. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073/pnas.2303165121Clev

Updated on:April 28,2024

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix

Updated on: December 28,2023

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix

Updated on:December 28,2023

Understanding Male Infertility: A New AI-Based Approach

This process is often carried out in specialized fertility clinics using microscopes and counting chambers by skilled embryologists.

Updated on: August 05,2024

Understanding Male Infertility: A New AI-Based Approach

This process is often carried out in specialized fertility clinics using microscopes and counting chambers by skilled embryologists.

Updated on:August 05,2024

COVID-19 viral load rebound can occur after VV116, nirmatrelvir-ritonavir

by Elana GotkineFor patients with mild-to-moderate COVID-19, viral load rebound and symptom rebound can occur after a standard five-day course of treatment with VV116 or nirmatrelvir-ritonavir, accord

Updated on: March 28,2024

COVID-19 viral load rebound can occur after VV116, nirmatrelvir-ritonavir

by Elana GotkineFor patients with mild-to-moderate COVID-19, viral load rebound and symptom rebound can occur after a standard five-day course of treatment with VV116 or nirmatrelvir-ritonavir, accord

Updated on:March 28,2024

Why you might not find your favorite cold meds at the pharmacy

by Levi Gadye,University of California, San FranciscoCredit: CC0 Public DomainIt's winter and many people are contending with the sniffles and coughs. For some, that means heading to the pha

Updated on: January 26,2024

Why you might not find your favorite cold meds at the pharmacy

by Levi Gadye,University of California, San FranciscoCredit: CC0 Public DomainIt's winter and many people are contending with the sniffles and coughs. For some, that means heading to the pha

Updated on:January 26,2024