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Breakthroughs
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In the drive to deprescribe, heartburn drug study teaches key lessons

In the drive to deprescribe, heartburn drug study teaches key lessons

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhether it's costs, safety risks, or "pill fatigue" they're trying to reduce, many health systems and clinics have star

In the drive to deprescribe, heartburn drug study teaches key lessons

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhether it's costs, safety risks, or "pill fatigue" they're trying to reduce, many health systems and clinics have star
Psilocybin found to reduce chronic pain in rats

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats
Smarter blood tests could deliver faster diagnoses and improved outcomes

Smarter blood tests could deliver faster diagnoses and improved outcomes

by Dalin Clark,Michigan State UniversitySmall molecule modulation of protein corona significantly enhances deep plasma proteome profiling. Credit: Mahmoudi GroupMedical professionals have long k

Smarter blood tests could deliver faster diagnoses and improved outcomes

by Dalin Clark,Michigan State UniversitySmall molecule modulation of protein corona significantly enhances deep plasma proteome profiling. Credit: Mahmoudi GroupMedical professionals have long k
New treatment options for advanced myelofibrosis and other blood malignancies show promise

New treatment options for advanced myelofibrosis and other blood malignancies show promise

byUniversity of Miami Leonard M. Miller School of MedicineCredit: CC0 Public DomainFew standard treatments have been available for advanced myelofibrosis, a bone marrow disorder characterized by

New treatment options for advanced myelofibrosis and other blood malignancies show promise

byUniversity of Miami Leonard M. Miller School of MedicineCredit: CC0 Public DomainFew standard treatments have been available for advanced myelofibrosis, a bone marrow disorder characterized by
Popular blood thinner associated with higher risk of bleeding complications

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu
Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

by AudioCure Pharma GmbHThe effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the cochlea. (B) Quantification of OHCs 14 d after noise exposure reveal

Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

by AudioCure Pharma GmbHThe effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the cochlea. (B) Quantification of OHCs 14 d after noise exposure reveal
Researchers identify brain center responsible for responses to rapid temperature change

Researchers identify brain center responsible for responses to rapid temperature change

by Win Reynolds,Northwestern UniversityTPN-IIIs display ON responses to temperature change. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42864-5We've all heard it:

Researchers identify brain center responsible for responses to rapid temperature change

by Win Reynolds,Northwestern UniversityTPN-IIIs display ON responses to temperature change. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42864-5We've all heard it:
Durvalumab and Tremelimumab before surgery in patients with HR+/HER2-negative breast cancer

Durvalumab and Tremelimumab before surgery in patients with HR+/HER2-negative breast cancer

by Impact Journals LLCAnalysis of immune cell subsets during neoadjuvant therapy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28567A new research paper was published inOncotarg

Durvalumab and Tremelimumab before surgery in patients with HR+/HER2-negative breast cancer

by Impact Journals LLCAnalysis of immune cell subsets during neoadjuvant therapy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28567A new research paper was published inOncotarg
Follow-up finds landmark steroid study remains safe 50 years on

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c
Mutation mapping shows errors in protein location are a common cause of disease

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of
Researchers work to preserve fertility for people undergoing gene therapy

Researchers work to preserve fertility for people undergoing gene therapy

byNational Institutes of HealthCD117-ADC depletes both human and non-human primate CD34+ cells.AEscalating doses of CD117-ADC were added to primary human and rhesus CD34+ cells in cu

Researchers work to preserve fertility for people undergoing gene therapy

byNational Institutes of HealthCD117-ADC depletes both human and non-human primate CD34+ cells.AEscalating doses of CD117-ADC were added to primary human and rhesus CD34+ cells in cu