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Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

byNYU Langone HealthCredit: CC0 Public DomainA cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.The study, led by re

Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

byNYU Langone HealthCredit: CC0 Public DomainA cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.The study, led by re
New software tool decodes cytokine 'language' of immune cells

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel
Biosimilar biologics do not always reduce out-of-pocket costs

Biosimilar biologics do not always reduce out-of-pocket costs

by Lori SolomonBiosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 inJ

Biosimilar biologics do not always reduce out-of-pocket costs

by Lori SolomonBiosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 inJ
New platform streamlines epitope comparison in antibody research

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib
Use of anticoagulant drug after aortic valve replacement lowers mortality risk, study finds

Use of anticoagulant drug after aortic valve replacement lowers mortality risk, study finds

by ByJay Furst,Mayo ClinicGraphical abstract. Credit:Mayo Clinic Proceedings(2023). DOI: 10.1016/j.mayocp.2023.08.012Patients who received the anticoagulant drug warfarin after biopr

Use of anticoagulant drug after aortic valve replacement lowers mortality risk, study finds

by ByJay Furst,Mayo ClinicGraphical abstract. Credit:Mayo Clinic Proceedings(2023). DOI: 10.1016/j.mayocp.2023.08.012Patients who received the anticoagulant drug warfarin after biopr
How memories are formed in the brain: A new role for the internal compass

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco
Plant compound used in traditional medicine may help fight tuberculosis

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for
Psilocybin found to reduce chronic pain in rats

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats
Microbiome changes in chronic liver disease highlight need for personalized treatment

Microbiome changes in chronic liver disease highlight need for personalized treatment

byKing's College LondonMicrobial diversity and community structure alterations by cirrhosis severity. Credit:Journal of Hepatology(2024). DOI: 10.1016/j.jhep.2024.09.046The bacte

Microbiome changes in chronic liver disease highlight need for personalized treatment

byKing's College LondonMicrobial diversity and community structure alterations by cirrhosis severity. Credit:Journal of Hepatology(2024). DOI: 10.1016/j.jhep.2024.09.046The bacte