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Breakthroughs
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Plozasiran reduces triglyceride levels by 74% at 24 weeks

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red
Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit
Researchers are building a cellular map of the musculoskeletal system

Researchers are building a cellular map of the musculoskeletal system

byUniversity of OxfordGeneralized workflow for generating a single-cell musculoskeletal atlas. To generate a single-cell atlas of the musculoskeletal system, samples are first acquired from musc

Researchers are building a cellular map of the musculoskeletal system

byUniversity of OxfordGeneralized workflow for generating a single-cell musculoskeletal atlas. To generate a single-cell atlas of the musculoskeletal system, samples are first acquired from musc
ADHD drug Zenzedi recalled over pill mixup

ADHD drug Zenzedi recalled over pill mixup

by Robin FosterThe maker of a drug used to treat ADHD and narcolepsy has recalled one lot of the medication after a pill mixup was discovered.The recallnotice, issued by Azurity Pharmaceuticals

ADHD drug Zenzedi recalled over pill mixup

by Robin FosterThe maker of a drug used to treat ADHD and narcolepsy has recalled one lot of the medication after a pill mixup was discovered.The recallnotice, issued by Azurity Pharmaceuticals
New software tool decodes cytokine 'language' of immune cells

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel
New tool unifies single-cell data for the global research community

New tool unifies single-cell data for the global research community

by Rachael Smith,Wellcome Trust Sanger InstituteGraphical Abstract. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.11.026A new methodology that allows for the categorization and organiz

New tool unifies single-cell data for the global research community

by Rachael Smith,Wellcome Trust Sanger InstituteGraphical Abstract. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.11.026A new methodology that allows for the categorization and organiz
Microglia act as a 'facilitator and stabilizer' for anesthesia, finds study

Microglia act as a 'facilitator and stabilizer' for anesthesia, finds study

byFudan UniversityThis figure summarizes the major findings of this study. Credit: He et al.,eLife, 2023Though it may be a surprise to the millions of people who undergo general anesthesia

Microglia act as a 'facilitator and stabilizer' for anesthesia, finds study

byFudan UniversityThis figure summarizes the major findings of this study. Credit: He et al.,eLife, 2023Though it may be a surprise to the millions of people who undergo general anesthesia
Plant compound used in traditional medicine may help fight tuberculosis

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for
Study suggests key to antipsychotic-drug–induced obesity

Study suggests key to antipsychotic-drug–induced obesity

by UTSouthwestern Medical CenterEffect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or a

Study suggests key to antipsychotic-drug–induced obesity

by UTSouthwestern Medical CenterEffect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or a
Lab tests show THC potency inflated on retail marijuana in Colorado

Lab tests show THC potency inflated on retail marijuana in Colorado

by Anna Schwabe,The ConversationCredit: Unsplash/CC0 Public DomainCannabis flower sold in Colorado claims to contain much more tetrahydrocannabinol, or THC, than it actually does, according to m

Lab tests show THC potency inflated on retail marijuana in Colorado

by Anna Schwabe,The ConversationCredit: Unsplash/CC0 Public DomainCannabis flower sold in Colorado claims to contain much more tetrahydrocannabinol, or THC, than it actually does, according to m
'Study drugs' shown to set the stage for other drug use and mental health decline

'Study drugs' shown to set the stage for other drug use and mental health decline

by Binghamton UniversityCredit: Pixabay/CC0 Public DomainTaking "study drugs" like Adderall without a diagnosis is not only dangerous in itself but can lead to other drug use and a decl

'Study drugs' shown to set the stage for other drug use and mental health decline

by Binghamton UniversityCredit: Pixabay/CC0 Public DomainTaking "study drugs" like Adderall without a diagnosis is not only dangerous in itself but can lead to other drug use and a decl