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Breakthroughs
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Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit
Exploring ferumoxytol: A new frontier in MRI contrast agents

Exploring ferumoxytol: A new frontier in MRI contrast agents

by Science China PressDuring the blood pool phase, it significantly shortens the T1and T2relaxation times of the blood, thus achieving bright blood effects in T1-weighted imaging and

Exploring ferumoxytol: A new frontier in MRI contrast agents

by Science China PressDuring the blood pool phase, it significantly shortens the T1and T2relaxation times of the blood, thus achieving bright blood effects in T1-weighted imaging and
Study discovers novel biomarker for vascular aging and neurodegeneration

Study discovers novel biomarker for vascular aging and neurodegeneration

by Melissa Rohman and Olivia Dimmer,Northwestern UniversityNotch3 deficiency results in vascular dysfunction due to impaired contractility. Immunofluorescence of phosphorylated myosin light chai

Study discovers novel biomarker for vascular aging and neurodegeneration

by Melissa Rohman and Olivia Dimmer,Northwestern UniversityNotch3 deficiency results in vascular dysfunction due to impaired contractility. Immunofluorescence of phosphorylated myosin light chai
Study finds AI can develop treatments to prevent 'superbugs'

Study finds AI can develop treatments to prevent 'superbugs'

byCleveland ClinicSchematic evolutionary simulation and tested optimization approaches. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073/pnas.2303165121Clev

Study finds AI can develop treatments to prevent 'superbugs'

byCleveland ClinicSchematic evolutionary simulation and tested optimization approaches. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073/pnas.2303165121Clev
Experimental pain med could give patients new option to opioids

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver
Study shows web app effective in determining access to statins without a prescription

Study shows web app effective in determining access to statins without a prescription

byAmerican College of CardiologyCredit: Pixabay/CC0 Public DomainUsing a web application to qualify individuals for treatment with a non-prescription statin closely matched the results of clinic

Study shows web app effective in determining access to statins without a prescription

byAmerican College of CardiologyCredit: Pixabay/CC0 Public DomainUsing a web application to qualify individuals for treatment with a non-prescription statin closely matched the results of clinic
Novel immunometabolism approach pioneers single-cell spatial metabolomics

Novel immunometabolism approach pioneers single-cell spatial metabolomics

by Jerry Grillo,Georgia Institute of TechnologyThe scSpaMet pipeline for integratedmetabolite and protein profiling at the single-cell resolution.aOverview of scSpaMet. Tissue

Novel immunometabolism approach pioneers single-cell spatial metabolomics

by Jerry Grillo,Georgia Institute of TechnologyThe scSpaMet pipeline for integratedmetabolite and protein profiling at the single-cell resolution.aOverview of scSpaMet. Tissue
New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

by Isabella Backman,Yale UniversityThe lab of Choukri Ben Mamoun, PhD (left), has a long-standing interest in fighting this tick-borne disease. Credit: Yale UniversityDrug-resistant babesiosis m

New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

by Isabella Backman,Yale UniversityThe lab of Choukri Ben Mamoun, PhD (left), has a long-standing interest in fighting this tick-borne disease. Credit: Yale UniversityDrug-resistant babesiosis m
Mouse study successfully regenerates thyroid glands in the spleen

Mouse study successfully regenerates thyroid glands in the spleen

by Nanjing University School of Life SciencesSchematic description of intra-splenic thyroid regeneration (left) and staining images of reconstructed thyroid tissues within the spleen (right). Credit:

Mouse study successfully regenerates thyroid glands in the spleen

by Nanjing University School of Life SciencesSchematic description of intra-splenic thyroid regeneration (left) and staining images of reconstructed thyroid tissues within the spleen (right). Credit:
Asia-Pacific gets new weapon in fight against drug-resistant TB

Asia-Pacific gets new weapon in fight against drug-resistant TB

Credit: CC0 Public DomainA faster and vastly more effective treatment for drug-resistant tuberculosis is being rolled out in the Asia-Pacific region, raising hopes of a "new era" in tackling

Asia-Pacific gets new weapon in fight against drug-resistant TB

Credit: CC0 Public DomainA faster and vastly more effective treatment for drug-resistant tuberculosis is being rolled out in the Asia-Pacific region, raising hopes of a "new era" in tackling
Scientists discover a framework in the brain for organizing the order of things

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix