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Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n
Different autism risk genes, same effects on brain development

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge
Gene editing precisely repairs immune cells

Gene editing precisely repairs immune cells

byMax Delbrück Center for Molecular MedicineMutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection,

Gene editing precisely repairs immune cells

byMax Delbrück Center for Molecular MedicineMutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection,
Chicken eggs could provide low-cost opportunities for cancer imaging research

Chicken eggs could provide low-cost opportunities for cancer imaging research

JANUARY 4, 2024byKing's College LondonComparison of in ovo and in vivo18F-FDG PET/CT imaging.aRepresentative in ovo18F-FDG PET/CT images 40–60 min p.i.. White arrows

Chicken eggs could provide low-cost opportunities for cancer imaging research

JANUARY 4, 2024byKing's College LondonComparison of in ovo and in vivo18F-FDG PET/CT imaging.aRepresentative in ovo18F-FDG PET/CT images 40–60 min p.i.. White arrows
Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com
Researchers discover a new role for a protein that helps form memories

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco
Study shows tendency for infection and bacterial flora explain caries

Study shows tendency for infection and bacterial flora explain caries

byUmea UniversityCredit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105001Researchers at Umeå University have for the first time been able to show that individual variation in susc

Study shows tendency for infection and bacterial flora explain caries

byUmea UniversityCredit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105001Researchers at Umeå University have for the first time been able to show that individual variation in susc
Study shows how genes in retina are regulated during development

Study shows how genes in retina are regulated during development

byNational Institutes of HealthThis image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a croc

Study shows how genes in retina are regulated during development

byNational Institutes of HealthThis image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a croc
Listen to your gut: Research discusses using microbiota analysis for precision health care

Listen to your gut: Research discusses using microbiota analysis for precision health care

by Sarah Small,Pennsylvania State UniversityIn a recently published paper, Pak Kin Wong discusses the methods discusses the methods available for incorporating microbiota analysis into clinical

Listen to your gut: Research discusses using microbiota analysis for precision health care

by Sarah Small,Pennsylvania State UniversityIn a recently published paper, Pak Kin Wong discusses the methods discusses the methods available for incorporating microbiota analysis into clinical
Study: This protein may be the 'glue' that helps COVID virus stick

Study: This protein may be the 'glue' that helps COVID virus stick

JANUARY 24, 2024byTulane UniversityCredit: CC0 Public DomainWhen SARS-CoV-2 enters the human body, the virus' spike protein binds to a cell, allowing the virus to infiltrate and begin replic

Study: This protein may be the 'glue' that helps COVID virus stick

JANUARY 24, 2024byTulane UniversityCredit: CC0 Public DomainWhen SARS-CoV-2 enters the human body, the virus' spike protein binds to a cell, allowing the virus to infiltrate and begin replic
Altering key ion channel found to protect against pancreatitis-associated acute lung injury

Altering key ion channel found to protect against pancreatitis-associated acute lung injury

JANUARY 11, 2024byAmerican Physiological SocietyCredit:Function(2023). DOI: 10.1093/function/zqad061A group of Chinese researchers has conducted a mouse study to determine the role o

Altering key ion channel found to protect against pancreatitis-associated acute lung injury

JANUARY 11, 2024byAmerican Physiological SocietyCredit:Function(2023). DOI: 10.1093/function/zqad061A group of Chinese researchers has conducted a mouse study to determine the role o
How corporate involvement in psychedelic research could threaten public safety

How corporate involvement in psychedelic research could threaten public safety

by Elena Koning, Elisa Brietzke and Marco Solmi,The ConversationCredit: Unsplash/CC0 Public DomainIn the mid-20th century,psychedelicswere deemed illegal substances with little medic

How corporate involvement in psychedelic research could threaten public safety

by Elena Koning, Elisa Brietzke and Marco Solmi,The ConversationCredit: Unsplash/CC0 Public DomainIn the mid-20th century,psychedelicswere deemed illegal substances with little medic