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Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)
3-D printed pill samples gut microbiome to aid diagnosis and treatment

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng
Researchers help design easy-to-open, child-resistant medicine bottle

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con
Poor trial results may prompt maker to pull ALS drug from market

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t
Vosoritide beneficial for children younger than 5 years with achondroplasia

Vosoritide beneficial for children younger than 5 years with achondroplasia

by Elana GotkineFor children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in

Vosoritide beneficial for children younger than 5 years with achondroplasia

by Elana GotkineFor children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in
Researchers shed light on the molecular causes of different functions of opioid receptors

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti
Wastewater sequencing reveals community and variant dynamics of the collective human virome

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan
Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps
Research finds T cell subset significantly expands in spleen and brain after virus infection

Research finds T cell subset significantly expands in spleen and brain after virus infection

byScience China Pressslc43a2+T cells differentiate and mature in spleen and are then transported to brain to trigger the production of cytokines involved in antiviral strategies against RG

Research finds T cell subset significantly expands in spleen and brain after virus infection

byScience China Pressslc43a2+T cells differentiate and mature in spleen and are then transported to brain to trigger the production of cytokines involved in antiviral strategies against RG
Research team discovers new way to generate human cartilage

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic