Researchers develop framework to identify molecules responsible for chemotherapy resistance

JANUARY 18, 2024byKarolinska InstitutetCredit:iScience(2024). https://www.cell.com/iscience/fulltext/S2589-0042(24)00128-7Researchers at Karolinska Institutet and SciLifeLab demonstr

Updated on: March 29,2024

Researchers develop framework to identify molecules responsible for chemotherapy resistance

JANUARY 18, 2024byKarolinska InstitutetCredit:iScience(2024). https://www.cell.com/iscience/fulltext/S2589-0042(24)00128-7Researchers at Karolinska Institutet and SciLifeLab demonstr

Updated on:March 29,2024

Nearly 40% of type 2 diabetes patients stop taking their second-line medication, finds study

byNorthwestern UniversityCredit: Unsplash/CC0 Public DomainMost patients with type 2 diabetes will end up needing to add a second-line medication after metformin—the go-to primary drug for gluco

Updated on: January 26,2024

Nearly 40% of type 2 diabetes patients stop taking their second-line medication, finds study

byNorthwestern UniversityCredit: Unsplash/CC0 Public DomainMost patients with type 2 diabetes will end up needing to add a second-line medication after metformin—the go-to primary drug for gluco

Updated on:January 26,2024

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on: January 26,2024

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on:January 26,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce

Updated on: April 06,2024

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce

Updated on:April 06,2024

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on: January 26,2024

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on:January 26,2024

Tackling antibiotic resistance when treating pneumonia

JANUARY 18, 2024byUniversity of LiverpoolSchematic summary of the molecular mechanisms in Pseudomonas aeruginosa associated with the observed phenotypic changes in the rabbit model. OprD-associa

Updated on: March 28,2024

Tackling antibiotic resistance when treating pneumonia

JANUARY 18, 2024byUniversity of LiverpoolSchematic summary of the molecular mechanisms in Pseudomonas aeruginosa associated with the observed phenotypic changes in the rabbit model. OprD-associa

Updated on:March 28,2024

New tool to analyze blood platelets holds major medical potential

by Carol Clark,Emory UniversityCredit: Pixabay/CC0 Public DomainA novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods cur

Updated on: January 02,2024

New tool to analyze blood platelets holds major medical potential

by Carol Clark,Emory UniversityCredit: Pixabay/CC0 Public DomainA novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods cur

Updated on:January 02,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on: April 06,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on:April 06,2024

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Updated on: March 06,2024

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Updated on:March 06,2024

Researchers uncover unexpected molecular pattern in fragile X syndrome

byPerelman School of Medicine at the University of PennsylvaniaCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.019Researchers have found new disrupted genes and an unexpected molecula

Updated on: March 29,2024

Researchers uncover unexpected molecular pattern in fragile X syndrome

byPerelman School of Medicine at the University of PennsylvaniaCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.019Researchers have found new disrupted genes and an unexpected molecula

Updated on:March 29,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on: April 27,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on:April 27,2024