Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Updated on: April 28,2024

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Updated on:April 28,2024

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on: March 14,2024

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on:March 14,2024

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Updated on: January 26,2024

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Updated on:January 26,2024

Researchers produce grafts that replicate the human ear

by Weill Cornell Medical CollegePictured is the intricate, left-ear plastic scaffold that was created on a 3D printer based on data from a person's ear, anterior view (left) and posterior vie

Updated on: April 06,2024

Researchers produce grafts that replicate the human ear

by Weill Cornell Medical CollegePictured is the intricate, left-ear plastic scaffold that was created on a 3D printer based on data from a person's ear, anterior view (left) and posterior vie

Updated on:April 06,2024

New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

by University of CologneThe picture shows neurons (magenta) born in the adult mouse hippocampus. Nuclei are stained cyan. The extending dendrites are important sites where mechanisms of plasticit

Updated on: April 06,2024

New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

by University of CologneThe picture shows neurons (magenta) born in the adult mouse hippocampus. Nuclei are stained cyan. The extending dendrites are important sites where mechanisms of plasticit

Updated on:April 06,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on: July 23,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on:July 23,2024

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on: January 09,2024

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on:January 09,2024

Green tea may help mitigate harm from hookah smoking, mouse study suggests

JANUARY 16, 2024byRUDN UniversityCredit:Molecules(2023). DOI: 10.3390/molecules28227502Many people consider hookah smoking to be less dangerous than smoking regular cigarettes. Yet h

Updated on: March 15,2024

Green tea may help mitigate harm from hookah smoking, mouse study suggests

JANUARY 16, 2024byRUDN UniversityCredit:Molecules(2023). DOI: 10.3390/molecules28227502Many people consider hookah smoking to be less dangerous than smoking regular cigarettes. Yet h

Updated on:March 15,2024

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Updated on: January 06,2024

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Updated on:January 06,2024

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Updated on: January 26,2024

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Updated on:January 26,2024

New study finds diabetes drug may reduce risk for colorectal cancer

byCase Western Reserve UniversityCredit: CC0 Public DomainA study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce

Updated on: January 26,2024

New study finds diabetes drug may reduce risk for colorectal cancer

byCase Western Reserve UniversityCredit: CC0 Public DomainA study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce

Updated on:January 26,2024

Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

This study introduces a novel framework for modeling organ health and biological aging using plasma proteomics, offering a more nuanced understanding of aging at the organ level.

Updated on: July 18,2024

Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

This study introduces a novel framework for modeling organ health and biological aging using plasma proteomics, offering a more nuanced understanding of aging at the organ level.

Updated on:July 18,2024