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Diabetes drug shows promise in protecting kidneys

Diabetes drug shows promise in protecting kidneys

byOsaka Metropolitan UniversityMore red areas in the kidney indicate higher oxygen levels. Credit: Osaka Metropolitan UniversityType 2 diabetes can lead to diabetic kidney disease, but a class o

Diabetes drug shows promise in protecting kidneys

byOsaka Metropolitan UniversityMore red areas in the kidney indicate higher oxygen levels. Credit: Osaka Metropolitan UniversityType 2 diabetes can lead to diabetic kidney disease, but a class o
Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide
Flies fed restricted diet in early adulthood found to live longer

Flies fed restricted diet in early adulthood found to live longer

byRIKENA model of lifespan extension by early Met restriction. Methionine restriction in young flies can induce MsrA and decrease MetSO level, leading to lifespan extension. This nutritional res

Flies fed restricted diet in early adulthood found to live longer

byRIKENA model of lifespan extension by early Met restriction. Methionine restriction in young flies can induce MsrA and decrease MetSO level, leading to lifespan extension. This nutritional res
Scientists say outdated diabetes drug still has something to offer

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil
Off-label use of a common antibiotic to treat muscular dystrophy

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads
Deep brain stimulation shows immediate improvement in arm and hand function post-brain injury, study finds

Deep brain stimulation shows immediate improvement in arm and hand function post-brain injury, study finds

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainDeep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or s

Deep brain stimulation shows immediate improvement in arm and hand function post-brain injury, study finds

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainDeep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or s
New insight into gene uncovers its link to incurable birth defect

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir
New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo
Study eases concern at antipsychotics use in pregnancy

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o
Research may offer relief to migraine sufferers

Research may offer relief to migraine sufferers

FEBRUARY 21, 2024by Josh Barney,University of VirginiaRoughly one in five women suffer from migraines, compared to fewer than one in 10 men. Credit: John DiJulia, University CommunicationsResear

Research may offer relief to migraine sufferers

FEBRUARY 21, 2024by Josh Barney,University of VirginiaRoughly one in five women suffer from migraines, compared to fewer than one in 10 men. Credit: John DiJulia, University CommunicationsResear