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Researchers halt progression of Parkinson's disease in mouse model

Researchers halt progression of Parkinson's disease in mouse model

NOVEMBER 14, 2023by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterGeneration and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar g

Researchers halt progression of Parkinson's disease in mouse model

NOVEMBER 14, 2023by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterGeneration and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar g
Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K
Genetics may influence the body's response to low oxygen, study finds

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity
Human cells building 'molecular highways' captured for first time

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the
Researchers make mice a more powerful tool to study a wide range of human diseases

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce
New insight into gene uncovers its link to incurable birth defect

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir
Developing standards for organ-on-a-chip research

Developing standards for organ-on-a-chip research

FEBRUARY 22, 2024by Jennifer Lauren Lee,National Institute of Standards and TechnologyOrgan-on-a-chip devices use tiny structures called microfluidic channels to bring small, controlled amounts

Developing standards for organ-on-a-chip research

FEBRUARY 22, 2024by Jennifer Lauren Lee,National Institute of Standards and TechnologyOrgan-on-a-chip devices use tiny structures called microfluidic channels to bring small, controlled amounts
Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease
Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or