Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov

Updated on: November 22,2024

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov

Updated on:November 22,2024

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Updated on: March 15,2024

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Updated on:March 15,2024

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on: April 06,2024

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on:April 06,2024

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Updated on: April 28,2024

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Updated on:April 28,2024

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car

Updated on: April 06,2024

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car

Updated on:April 06,2024

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p

Updated on: July 06,2024

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p

Updated on:July 06,2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on: April 28,2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on:April 28,2024

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

Updated on: March 14,2024

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

Updated on:March 14,2024

Critical Review of the Mechanisms by Which Tumor-Derived Exosomes Induce Immunosuppressive Macrophages through Metabolic Reprogramming

Updated on: September 13,2024

Critical Review of the Mechanisms by Which Tumor-Derived Exosomes Induce Immunosuppressive Macrophages through Metabolic Reprogramming

Updated on:September 13,2024

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on: March 30,2024

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on:March 30,2024

Research may offer relief to migraine sufferers

FEBRUARY 21, 2024by Josh Barney,University of VirginiaRoughly one in five women suffer from migraines, compared to fewer than one in 10 men. Credit: John DiJulia, University CommunicationsResear

Updated on: March 30,2024

Research may offer relief to migraine sufferers

FEBRUARY 21, 2024by Josh Barney,University of VirginiaRoughly one in five women suffer from migraines, compared to fewer than one in 10 men. Credit: John DiJulia, University CommunicationsResear

Updated on:March 30,2024