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Breakthroughs
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Ehrapy: A new open-source tool for analyzing complex health data

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t
Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K
Researchers discover a potential cause of Parkinson's disease

Researchers discover a potential cause of Parkinson's disease

MAY 5, 2023byUniversity of HelsinkiAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research groupThere are currently 8 million patients with Parkinson's disease in the

Researchers discover a potential cause of Parkinson's disease

MAY 5, 2023byUniversity of HelsinkiAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research groupThere are currently 8 million patients with Parkinson's disease in the
Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th
New resource maps gene-disease links across common conditions, paving the way for personalized medicine

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
Bridging diet, microbes, and metabolism: Implications for metabolic disorders

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or
Rapid drug test to provide patients with better care

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p
Human cells building 'molecular highways' captured for first time

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the