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Study provides molecular blueprint of spinal circuits governing locomotor speed

Study provides molecular blueprint of spinal circuits governing locomotor speed

byKarolinska InstitutetSingle-cell RNAseq of GFP+neurons in isl1a:GFP and chx10:GFP transgenic lines. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01479-1Researche

Study provides molecular blueprint of spinal circuits governing locomotor speed

byKarolinska InstitutetSingle-cell RNAseq of GFP+neurons in isl1a:GFP and chx10:GFP transgenic lines. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01479-1Researche
Cellular 'waste product' rejuvenates cancer-fighting immune cells

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh
New study sheds light on how our brains perceive—or fail to perceive—what we see

New study sheds light on how our brains perceive—or fail to perceive—what we see

byAllen Institute for Brain ScienceCredit: Magoi from PexelsA newstudyinNature Neuroscienceon 'visual masking' sheds light on how we 'unsee' things and po

New study sheds light on how our brains perceive—or fail to perceive—what we see

byAllen Institute for Brain ScienceCredit: Magoi from PexelsA newstudyinNature Neuroscienceon 'visual masking' sheds light on how we 'unsee' things and po
Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155
Researchers identify and manipulate neural circuits for risk/reward decision-making in primates

Researchers identify and manipulate neural circuits for risk/reward decision-making in primates

by Spyros Goulas, Institute for the Advanced Study of Human Biology (ASHBI)Bananas represent the reward and the crocodile represents the risk. The blue path is a low risk-low return decision, while th

Researchers identify and manipulate neural circuits for risk/reward decision-making in primates

by Spyros Goulas, Institute for the Advanced Study of Human Biology (ASHBI)Bananas represent the reward and the crocodile represents the risk. The blue path is a low risk-low return decision, while th
Lifespan increases in mice when specific brain cells are activated, study finds

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n
Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02
Demystifying a key receptor in substance use and neuropsychiatric disorders

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine
How memories are formed in the brain: A new role for the internal compass

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco
Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic
Comparing human and mouse Purkinje cells to better understand human brain complexity

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai
How a suction cup delivers medications to the bloodstream

How a suction cup delivers medications to the bloodstream

by Christoph Elhardt,ETH ZurichThe suction cup contains active ingredients and can be pressed onto the lining of the check with two fingers. Credit: Luo Z et al. 2023, editedResearchers at ETH Z

How a suction cup delivers medications to the bloodstream

by Christoph Elhardt,ETH ZurichThe suction cup contains active ingredients and can be pressed onto the lining of the check with two fingers. Credit: Luo Z et al. 2023, editedResearchers at ETH Z