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Allergy&Clinical immunology
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FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

byUniversity of California, Los AngelesUCLA's Dr. Donald Kohn with Marley Gaskins and her mother, Tamara Hogue. Marley was the first patient to enroll in the LAD-l clinical trial in 2019. Credit:

FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

byUniversity of California, Los AngelesUCLA's Dr. Donald Kohn with Marley Gaskins and her mother, Tamara Hogue. Marley was the first patient to enroll in the LAD-l clinical trial in 2019. Credit:
How T cells amplify signals: New study reveals key molecular switch

How T cells amplify signals: New study reveals key molecular switch

byDelthia Ricks, Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDSignaling is fundamental to how cells

How T cells amplify signals: New study reveals key molecular switch

byDelthia Ricks, Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDSignaling is fundamental to how cells
Orthodontics researchers evaluate microplastics' effect on immune system

Orthodontics researchers evaluate microplastics' effect on immune system

by Laurie Kaiser,University at BuffaloCharacterization of orthodontic-derived plastic particles. Credit:Progress in Orthodontics(2026). DOI: 10.1186/s40510-026-00608-3In a new study, orthodontics rese

Orthodontics researchers evaluate microplastics' effect on immune system

by Laurie Kaiser,University at BuffaloCharacterization of orthodontic-derived plastic particles. Credit:Progress in Orthodontics(2026). DOI: 10.1186/s40510-026-00608-3In a new study, orthodontics rese
Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies

Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies

by Uta von der Gönna, Jena UniversityCredit:Science Advances(2026). DOI: 10.1126/sciadv.aea0773An international research team has succeeded in elucidating key immunological and biochemical mechanisms

Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies

by Uta von der Gönna, Jena UniversityCredit:Science Advances(2026). DOI: 10.1126/sciadv.aea0773An international research team has succeeded in elucidating key immunological and biochemical mechanisms
Algae-derived sugars show anti-inflammatory effects and support skin repair

Algae-derived sugars show anti-inflammatory effects and support skin repair

byEstonian Research CouncilAmal D. Premarathna. Credit: Amal D. PremarathnaChronic wounds affect approximately 2% of the population in developed countries. Existing treatments are expensive and may ca

Algae-derived sugars show anti-inflammatory effects and support skin repair

byEstonian Research CouncilAmal D. Premarathna. Credit: Amal D. PremarathnaChronic wounds affect approximately 2% of the population in developed countries. Existing treatments are expensive and may ca
No link found between childhood atopic dermatitis and markers of cardiovascular risk

No link found between childhood atopic dermatitis and markers of cardiovascular risk

by Lori SolomonAtopic dermatitis (AD) during childhood is not associated with increases in markers of cardiovascular risk, according to a study published online March 24 inJAMA Network Open.Morgan Ye,

No link found between childhood atopic dermatitis and markers of cardiovascular risk

by Lori SolomonAtopic dermatitis (AD) during childhood is not associated with increases in markers of cardiovascular risk, according to a study published online March 24 inJAMA Network Open.Morgan Ye,
Reactivation of dormant regulatory T cells alleviates asthma symptoms in mice

Reactivation of dormant regulatory T cells alleviates asthma symptoms in mice

byRockefeller University PressTreatment with KQS-1 (right) significantly reduces the amount of inflammation observed in tissue samples taken from asthmatic mice in comparison to untreated controls (le

Reactivation of dormant regulatory T cells alleviates asthma symptoms in mice

byRockefeller University PressTreatment with KQS-1 (right) significantly reduces the amount of inflammation observed in tissue samples taken from asthmatic mice in comparison to untreated controls (le
Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds

Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds

byKeio UniversityMultiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS). Wh

Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds

byKeio UniversityMultiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS). Wh
Scientists capture early stages of immune response inside cells

Scientists capture early stages of immune response inside cells

by Ali Sundermier,SLAC National Accelerator LaboratoryScientists captured, for the first time, the formation of an immune signaling complex inside intact human cells. The results provide a closer look

Scientists capture early stages of immune response inside cells

by Ali Sundermier,SLAC National Accelerator LaboratoryScientists captured, for the first time, the formation of an immune signaling complex inside intact human cells. The results provide a closer look
How some autoantibodies contribute to clots: The C4BP link and a path to treatment

How some autoantibodies contribute to clots: The C4BP link and a path to treatment

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to blood

How some autoantibodies contribute to clots: The C4BP link and a path to treatment

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to blood