Medical scientific research
Study confirms how RNA chemical modifications benefit HIV-1

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate
Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n
Body mapping links responses to music with degree of uncertainty and surprise

Body mapping links responses to music with degree of uncertainty and surprise

byCell PressParticipants clicked on an image of the body to show where they most felt the music. The more clicks, the stronger the sensation (shown by the blue-low to red-high gradient). Body im

Body mapping links responses to music with degree of uncertainty and surprise

byCell PressParticipants clicked on an image of the body to show where they most felt the music. The more clicks, the stronger the sensation (shown by the blue-low to red-high gradient). Body im
Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX
Working conditions can explain educational differences in heart disease mortality

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve
Researchers shed light on the molecular causes of different functions of opioid receptors

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti
Study finds embryos in hungry mouse moms postpone development

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,
Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide