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Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur
New therapies offer effective treatment for managing Tourette syndrome

New therapies offer effective treatment for managing Tourette syndrome

byKennedy Krieger InstituteCredit: Pixabay/CC0 Public DomainResearchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Thei

New therapies offer effective treatment for managing Tourette syndrome

byKennedy Krieger InstituteCredit: Pixabay/CC0 Public DomainResearchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Thei
Scientists identify mutations that cause inherited kidney disease

Scientists identify mutations that cause inherited kidney disease

byAtrium Health Wake Forest BaptistCredit:Kidney International(2023). DOI: 10.1016/j.kint.2023.11.021Genetic changes or mutations can cause hereditary kidney disease, which can event

Scientists identify mutations that cause inherited kidney disease

byAtrium Health Wake Forest BaptistCredit:Kidney International(2023). DOI: 10.1016/j.kint.2023.11.021Genetic changes or mutations can cause hereditary kidney disease, which can event
Pancreas cells in people who have died show significant signs of stress

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
HIV: Early treatment is one key to remission

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-
Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit
Study suggests statins could help fight gum disease

Study suggests statins could help fight gum disease

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainCould taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cult

Study suggests statins could help fight gum disease

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainCould taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cult
COVID-19 hitches a ride on mucus to spread deep into lungs, live imaging shows

COVID-19 hitches a ride on mucus to spread deep into lungs, live imaging shows

by Olivia Dimmer,Northwestern UniversityInverted ALI culture models support MCC. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53791-4The COVID-19 virus spreads via muc

COVID-19 hitches a ride on mucus to spread deep into lungs, live imaging shows

by Olivia Dimmer,Northwestern UniversityInverted ALI culture models support MCC. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53791-4The COVID-19 virus spreads via muc
Working conditions can explain educational differences in heart disease mortality

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve
Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI